Echinacoside

Contact:jerry.he@wecistanche.com

Echinacoside in Cistanche Extract is a great ingredient with many functions:

One. Function and applications of Echinacoside in different products.

1. Establishment of the concurrent experimental model of osteoporosis combined with Alzheimer's disease in rat and the dual-effects of echinacoside and acteoside from Cistanche tubulosa.

2. Echinacoside prevents hypoxic pulmonary hypertension by regulating the pulmonary artery function.

3. Echinacoside Isolated from Cistanche tubulosa Putatively Stimulates Growth Hormone Secretion via Activation of the Ghrelin Receptor.

4. Echinacoside, an Active Constituent of Cistanche Herba, Exerts a Neuroprotective Effect in a Kainic Acid Rat Model by Inhibiting Inflammatory Processes and Activating the Akt/GSK3β Pathway.

5. Protective effects of echinacoside against anoxia/reperfusion injury in H9c2 cells via up-regulating p-AKT and SLC8A3.

6. Echinacoside, an active constituent of <i>Herba Cistanche</i>, suppresses epileptiform activity in hippocampal CA3 pyramidal neurons.

7. Echinacoside Induces Apoptosis in Human SW480 Colorectal Cancer Cells by Induction of Oxidative DNA Damages.

8. Echinacoside Alleviates UVB Irradiation-Mediated Skin Damage via Inhibition of Oxidative Stress, DNA Damage, and Apoptosis.

9. Echinacoside Alleviates Hypoxic-Ischemic Brain Injury in Neonatal Rat by Enhancing Antioxidant Capacity and Inhibiting Apoptosis.

10. Antioxidant effect

Comparing the inhibitory effects of alkyl amides, polysaccharides and caffeic acid derivatives in ECH on the oxidation of human low-density lipoproteins in vitro, it is found that the combination of ECH and alkyl amides or macromolecular polysaccharides has a synergistic antioxidant effect, that is, the biological effect of ECH. The activity is synergistically produced by a variety of ingredients in its preparation. ECH plays an important role in protecting DNA from damage. In short, a large number of studies have shown that ECH is a good natural antioxidant.

11. Neuroprotection

ECH has a significant protective effect on the apoptosis of nerve cells SHSY5Y induced by tumor necrosis factor (TNF-α). Its mechanism is to maintain the function of mitochondria through antioxidant effects, reduce the level of intracellular reactive oxygen species, and inhibit the activity of caspase-3 And maintain the high-energy state of mitochondrial membrane potential. Because ECH has strong anti-apoptotic activity, it may be used to treat neurodegenerative and nervous system diseases including neuronal apoptosis.

12. Improve learning and memory

ECH has an anti-aging effect, and its mechanism is that it can significantly inhibit O2−•, OH• and other free radicals, and at the same time can increase the activity of GSH-Px and SOD, and reduce the content of MDA. The memory of mice is improved by inhibiting the activity of MAO. The results of this study indicate that the anti-lipid peroxidation and improving aging effects of ECH are related to its antioxidant activity. ECH may improve the learning and memory ability of SAM-P/8 mice by improving the function of the central cholinergic system, increasing the total antioxidant capacity, promoting protein and nucleic acid synthesis, and regulating the immune state.

13. Anti-inflammatory effect

14. Anti-tumor effect

15. Liver protection

Verbascum glycosides, isoverbasin glycosides, 2'-acetyl verbascum glycosides and ECH obtained from Cistanche deserticola have significant hepatoprotective activities.

16. Immunomodulatory effect

Phenylethanol glycosides have regulatory effects and immunosuppressive activities of the human immune system. Phenylethanol glycoside compounds can enhance the value of hemolysin and fibrinogen, and have a strengthening effect on the body's non-specific immune function.

Two. What is Echinacoside content in Wecistanche extract product?

We have ten kinds of specifications as blow you can check.Echinacoside content is from 10% to 40%.We extracted by using ethanol.We are biggest cistanche extract manufacture in the world.

Cistanche Extract Specification Sheet

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