What You Must Know About Polycystic Kidney Disease

Factors of having polycystic kidney disease

The first is genetic factors. Medical research has found that polycystic kidney disease is closely related to heredity. Followed by environmental factors, including physical, chemical, and biological factors. In the process of embryonic development, due to some reasons, the connection between the renal tubules and the collecting ducts will be poor, and the secretion of urine will be hindered during the excretion process, resulting in the formation of some retention cysts in the renal tubules, and finally the development of polycystic kidneys.

Click to Cistanche tubulosa Tablets and health benefits of cistanche for kidney disease

Polycystic kidney and kidney cysts

Kidney cysts are generally solitary, the number of cysts increases with age, and the size of the cysts also increases with age. Some scholars believe that renal cysts are benign lesions, and cancerous ones are extremely rare. Kidney cysts are more common in the upper part of the kidney and are more common in the right kidney. Generally speaking, renal cysts are asymptomatic and are mostly found by ultrasound during routine physical examination. However, if there is bleeding in the cyst, or if there is an infection in the cyst, severe pain can occur at the cyst site. Polycystic kidney disease is characterized by cystic expansion of normal nephrons, cysts of different sizes in the kidney, and the kidneys being enlarged to varying degrees, most of which are bilateral.

Early symptoms of polycystic kidney disease

Patients with polycystic kidney disease often have symptoms of hypertension, hematuria, waist pain, and renal insufficiency. The most common sign is renal mass. People with the above symptoms should go to the hospital for corresponding examinations. At the same time, people with a family history of polycystic kidney disease must be vigilant and should go to the hospital to screen for the disease. Kidney B-ultrasound is the easiest, safest, and most economical way to screen for polycystic kidney disease. Difference.

Treatment options for polycystic kidney disease

1. Stable treatment

If the patient's general condition is good, the lumbar mass has not increased significantly, and the renal function has not been significantly damaged, the patient can temporarily not undergo surgery. By controlling blood pressure, treating hyperlipidemia, vasopressin receptor antagonists, and regular review, stable condition.

2. Anti-infective treatment

Due to the abnormal renal anatomy and poor urinary flow in patients with polycystic kidney disease, urinary tract infections are prone to occur. In severe cases, systemic infection symptoms may occur. Conventional cephalosporin antibiotics are ineffective. Fat-soluble antibiotics such as cyclopropane are found in our center. Floxacin, metronidazole, etc. have a better therapeutic effect on such patients.

3. Kidney transplant surgery

Kidney transplantation is the most ideal treatment for patients with end-stage polycystic kidney disease.

Most patients with polycystic kidney disease gradually develop renal insufficiency after the age of 40, but it does not mean that kidney transplantation should be performed immediately after the diagnosis of polycystic kidney disease, because some patients have relatively stable renal function and have not developed uremia. Therefore, kidney transplantation should be performed only when it is clear that the kidney function has reached the stage of uremia.

Indications for polycystic kidney resection

At present, many transplant centers adopt the treatment method of preserving polycystic kidneys and performing kidney transplantation. A small number of patients with clear surgical indications have unilateral or bilateral polycystic kidneys removed before transplantation, and patients who have polycystic kidneys removed after transplantation are rare.  The clinically recognized indications of polycystic kidney transplantation for renal transplantation include severe pain and discomfort, repeated hematuria, repeated upper urinary tract infections, severe abdominal distension, giant polycystic kidney disease affecting the placement of the transplanted kidney, and suspected malignant renal tumors.

Precautions after kidney transplantation

In patients with end-stage polycystic kidney disease, due to long-term anuria, anemia, hypoalbuminemia, poor nutritional status, severe cyst fluid accumulation, and obvious symptoms of edema, postoperative gastrointestinal function recovery should be promoted as soon as possible to strengthen postoperative gastrointestinal nutrition. Postoperative complications also need to be paid attention to: such as incision complications, bleeding infection of surgical wounds, refractory ascites, abdominal organ injury, pulmonary infection, and bleeding infection of residual polycystic kidney disease. In addition, it is particularly important to note that after transplantation, follow the doctor's advice to take immunosuppressive drugs on time and in the amount. Excessive immunosuppression is often the most common cause of many postoperative complications.

Cistanche is a natural herb for polycystic kidney disease

Cistanche is one of the nine Chinese fairy herbs. It is as famous as ginseng, Ganoderma lucidum, and Cordyceps Sinensis. The medicinal effect of Cistanche is listed as the top grade in the "Shen Nong's Classic of Materia Medica", so it has been used as a traditional Chinese medicinal material in China for more than 2,000 years. Modern pharmacological activity studies have shown that Cistanche is rich in phenylethanoid glycosides with verbascoside and echinacoside as the iconic components, which can increase the proliferation rate of human kidney cells by 8-10 times. Cistanche can protect renal tubular cells, prevent kidney interstitial lesions, slow down the rate of nephritis, and also effectively prevent secondary bacterial infections in patients with chronic kidney failure and polycystic kidney disease.

for more information:ali.ma@wecistanche.com