-
28
May, 2024
A State Of The Art Of Antioxidant Properties Of Curcuminoids in Neurodegenera...
Abstract: Neurodegenerative diseases represent a set of pathologies characterized by an irreversible and progressive, and a loss of neuronal cells in specific areas of the brain. Oxidative phosphor...
-
27
May, 2024
Aptamer Applications in Neuroscience Part 4
PET is another highly effective imaging method used in clinical diagnostics as it can provide tomographic resolution at any tissue depth. PET scan, positron emission tomography, is a medical imagin...
-
27
May, 2024
Aptamer Applications in Neuroscience Part 3
3.2.2. PD Therapeutics To relieve the symptoms of Parkinson's disease (PD), two 58-nucleotide-long DNA aptamers specific for human α-syn were selected with Kd values in the nanomolar range (2.4 nM ...
-
27
May, 2024
Aptamer Applications in Neuroscience Part 2
Another neurotransmitter, serotonin, plays a role in neuromodulation activities affecting sleep, aggression, appetite, and sexual activity. It is produced in different body parts, such as the brain...
-
27
May, 2024
Aptamer Applications in Neuroscience Part 1
Abstract: Being the predominant cause of disability, neurological diseases have received much attention from the global health community. The nervous system is an important part of the human body. ...
-
24
May, 2024
Redox Effects Of Molecular Hydrogen And Its Therapeutic Efficacy in The Treat...
6. Effects of Molecular Hydrogen on Animal and Human Models of Neurodegenerative Diseases PD is caused by the death of dopaminergic neurons at the SNpc of the midbrain and is the second most common...
-
24
May, 2024
Redox Effects Of Molecular Hydrogen And Its Therapeutic Efficacy in The Treat...
Abstract: Oxidative stress (OS) and neuroinflammatory stress affect many neurological disorders. Despite the clinical significance of oxidative damage in neurological disorders, still, no effective...
-
24
May, 2024
The Therapeutic Role Of Ketogenic Diet in Neurological Disorders Part 4
Inflammation and high concentrations of substance P cause arterial dilation and headache, which is the most characteristic symptom of a migraine attack [189]. Hypoglycaemia is shown to prolong the ...
-
23
May, 2024
The Therapeutic Role Of Ketogenic Diet in Neurological Disorders Part 3
Although the hypothesis of the involvement of the microbiota in the pathogenesis of many diseases has been established for some time, studies on the effects of the ketogenic diet on the composition...
-
23
May, 2024
The Therapeutic Role Of Ketogenic Diet in Neurological Disorders Part 2
2.3. The Impact of the Ketogenic Diet on Insulin Signalling Insulin is a hormone produced by pancreatic β cells that increases glucose uptake by the cells, thereby reducing blood glucose levels [60...
-
23
May, 2024
The Therapeutic Role Of Ketogenic Diet in Neurological Disorders Part 1
Abstract: The ketogenic diet (KD) is a high-fat, low-carbohydrate, and adequate-protein diet that has recently gained popularity in the context of neurological diseases (NDs). With the changes in m...
-
22
May, 2024
Neuroglial Senescence, α-Synucleinopathy, And The Therapeutic Potential Of Se...
Concerning PD pathology, activated caspase-1 cleaves αsynuclein into a truncated form that is highly prone to forming the insoluble aggregates characteristic of Lewy bodies (Wang et al., 2016). As ...