A Behavior That Pushes People To Uremia And Kidney Disease, You May Repeat It Every Day

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Kidney Line often says to his friends: People who eat whole grains will not get sick. Reconciliation with the disease and maintaining a positive and optimistic attitude are the best medicines to promote the recovery of kidney disease.

But some people think that this is just a comforting word. What is the relationship between a person's mood and mental state and the recovery of kidney disease?

No, a recent large-scale study published in the famous kidney disease journal CJASN reminds us that emotions are really closely related to kidney disease! If a person is often in a depressed state, such as being depressed, annoying, and boring to live, the deterioration of renal function will be significantly accelerated.

This is a prospective longitudinal cohort study, including a total of 4763 middle-aged and elderly people, their baseline estimated glomerular filtration rate (eGFR) > 60, to observe the relationship between their depressive symptoms and renal function decline, median follow-up For 4 years, the researchers defined rapid decline in renal function as a decrease in the annual glomerular filtration rate of ≥5ml/min/1.73m2.

Explain here what the concept of a decline in GFR of ≥5 per year is. End-stage renal disease (commonly known as "uremia") refers to the irreversible drop in the glomerular filtration rate below 15, and a person's glomerular filtration rate drops to 10 and is almost on dialysis. If the basic glomerular filtration rate is 60 → GFR calculation tool, it will drop by 5 every year, (60-10) ÷ 5=10, that is to say, dialysis will be required in 10 years, which is very fast!

The study regularly gave participants a score on the CES-D Depression Scale, or you could score yourself, with higher scores indicating more severe depression. Basically no, score 0; occasionally (only 1 or 2 days a week), score 1; sometimes (think about half of the week), score 2; almost every day, score 3, Then add up the scores for all items.

As a result, the researchers found that people with more depression (scores ≥10) had a 39% increased risk of rapid decline in kidney function compared to people who were less depressed (scores <10).

Also, particularly high depression scores (≥21 points) were associated with a significantly higher risk of rapid decline in renal function.

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Why is this so?

There are many factors. First, previous studies have shown that depression is associated with higher levels of inflammation in the body. A depressed state activates autoimmunity and increases the level of inflammatory cytokines in the body, which may be one of the reasons why a depressive state promotes renal sclerosis and fibrosis and accelerates the decline of renal function.

In addition, the depressed state also reduces the sensitivity of the immune system to glucocorticoids and damages the immune system.

In addition to the physical impact, depression can also affect the patient's behavior, such as not wanting to take care of themselves, lack of motivation to eat well, unwilling to participate in physical activities, loss of confidence in treatment, not wanting to see a doctor regularly, and tend to seek Folk remedies, secret recipes and deviating from regular treatment, etc., these factors may lead to faster progression of renal function.

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Everyone has dark moments in life, and suffering from illness is a major test. The existing medical model usually ignores or even ignores the psychological distress of patients. Kidney disease, in particular, is a difficult disease in itself, and it tests people over and over again. In addition, many people don't understand it, and they look at it with "tinted glasses", which makes the patient feel a lot of psychological pressure and cannot tell outsiders.

Kidney Online hopes to tell everyone that even if you are sick and not so "perfect", no one can replace you. No one is more important than you, and the will of the world must be presented through you as a carrier. Now that the disease has come, don't make cruel and severe self-attacks every day, no matter what the reality is, don't be the first person to give up on yourself.

You can go to a psychiatrist, and if necessary, you can take medicine to help you through. Go to the great people in the books and see how they spent their bad times; you can also find patient organizations to help and support each other.

In a word, illness is not your fault. Heaven and earth are not benevolent and all things are dogs. Sickness is a natural thing, and no one can escape, sooner or later.

When you feel depressed, you can lie down, step back, hide, don’t work hard, or fail, but don’t give up on yourself, because everything in the world adds up to you. As long as you don't give up, kidney disease can't hit you. All you need is to give yourself more patience and courage and cooperate with treatment, and life will gradually improve.

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