Are There Any Drugs That Work Best For Parkinson's Disease?
Apr 29, 2022
Parkinson's patients often complain that they have a dry mouth and bitter taste after taking some medicines, dizziness, and even hallucinations. . As the saying goes: "Drugs are poisonous." For Parkinson's patients who need long-term medication, the side effects of drugs should be the most worrying and most concerning issue for all Parkinson's patients. So today, Dr. Wang Shilong will briefly check the four commonly used Parkinson's drugs and their side effects for you. After fully understanding, you can choose the best treatment drugs according to your personal needs, but do not use drugs without authorization or change the dosage and time of drug use.
Click to Cistanche tubulosa examine and cistanche tubulosa side effects for Parkinson's disease
1. Dopaszil tablets
more common side effects
【Heart】: Occasionally arrhythmia.
[Vascular]: Occasional orthostatic hypoglycemia. Orthostatic hypoglycemia usually improves by reducing the dose of Madopar.
【Gastrointestinal】: Nausea, vomiting, and diarrhea have been reported during the administration of Medopa. Gastrointestinal adverse reactions occurred mainly at the beginning of treatment
2. Amantadine Hydrochloride Tablets
The main side effects are dizziness, insomnia and nervousness, nausea, vomiting, anorexia, dry mouth, and constipation. Occasionally depression, anxiety, hallucinations, confusion, ataxia, headache, and rare seizures. Leukopenia and neutropenia are rare.
3, levodopa tablets
Common adverse reactions are nausea, vomiting, orthostatic hypotension, abnormal involuntary movements of the head, face, tongue, upper extremities, and upper body, mental depression, and dysuria. Less common adverse reactions are hypertension, arrhythmia, and hemolytic anemia.
4. Pramipexole Hydrochloride Tablets
Common adverse reactions include abnormal dreaming, confusion, constipation, delusions, dizziness, dyskinesia, fatigue, hallucinations, headache, hyperkinesia, hypotension, increased appetite (bulimia, bulimia), insomnia, libido Disorders, nausea, peripheral edema, paranoia; pathological gambling, hypersexuality, or other abnormal behavior; lethargy, weight gain, sudden sleep onset; itching, rash, and other allergic symptoms.
Under the guidance of a doctor, patients with Parkinson's disease choose the appropriate drug treatment plan according to the condition. During taking the drug, you must follow the doctor's instructions, pay attention to the relevant contraindications and matters, and you must not arbitrarily suspend the drug or increase or decrease the dose of the drug at will. The above are just the more common side effects of most Parkinson's disease drugs, and the specific phenomenon must still vary from person to person and from drug to drug.
Effect of Cistanche on Parkinson's disease
Echinacoside in Cistanche can improve the behavioral defects of MPTP-induced PD model mice, increase the striatal dopamine (DA) metabolite 3,4-dihydroxypheny lacetic acid (3,4-dihydroxypheny lacetic acid, DOPAC), and high Vanillic acid (homovanillic acid, HVA) content significantly inhibits the apoptosis of cerebellar granule neurons caused by the activation of caspase-3 and caspase-8; reduces the overexpression of biliverdin reductase B in the brain of Parkinson's patients, suggesting Echinacoside reduce the increase of biliverdin reductase B caused by oxidative stress through its anti-oxidative stress effect, and protect dopaminergic neurons from oxidative stress damage. Its neuroprotective mechanism may be similar to that of bile Decreased levels of chlorophyll reductase B are related; to the reduction of dopaminergic neurons and dopamine transporters in the substantia nigra of the brain of patients with Parkinson's disease, and can enhance neurotrophic factor [neurotrophic factor, NTF. brain-derived neurotrophic factor, BDNF) and nerves The activity and protein expression level of glial cell line-derived neurotrophic factor (GDNF) derived from the glial cell line can reduce the ratio of mRNA and protein in apoptosis and Bax/Bcl-2. In addition, echinacoside can significantly increase the content of dopamine, DOPAC, and HVA in the extracellular fluid of the striatum of patients with Parkinson's disease.
for more information:ali.ma@wecistanche.com
