Knowing The Kidneys, Understanding Chronic Kidney Disease

The prevalence of chronic kidney disease in my country is 10.8%, the number of patients exceeds 100 million, and one in every 100 chronic kidney disease patients has developed uremia. The prevention and treatment of chronic kidney disease are facing severe challenges, and its disability and mortality rate ranks first among all chronic diseases. Chronic kidney disease has become another "silent killer" that threatens human life and health after cardiovascular and cerebrovascular diseases, tumors, and diabetes.

In 2006, the International Society of Nephrology and the International Federation of Kidney Funds jointly proposed that the second Thursday of March each year be designated as "World Kidney Day", aiming to raise awareness of chronic kidney disease and related cardiovascular disease and mortality. awareness and emphasis on early detection and prevention of chronic kidney disease. This year's theme is "Actively Facing Kidney Disease and Sharing a Wonderful Life", emphasizing that all kidney disease patients should actively accept the facts of the disease, actively regulate the treatment and scientific self-management, and work with doctors to overcome kidney disease and enjoy a better life.

Contact: joanna.jia@wecistanche.com / WhatsApp: 008618081934791

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What is chronic kidney disease?

The current international definition of chronic kidney disease is chronic kidney structure and dysfunction caused by various causes (history of kidney damage greater than 3 months), including normal and abnormal glomerular filtration rate pathological damage, blood or urine Abnormal fluid composition, abnormal imaging examination, or unexplained decrease in glomerular filtration rate (<60ml/min·1.73m2) for more than 3 months. In addition to uncontrollable factors such as heredity, age, and low birth weight, chronic glomerulonephritis, hypertension, diabetes, hyperuricemia, gout, obesity, and drug abuse are the main causes of chronic kidney disease.

Common causes of chronic kidney disease in my country

1. Diabetes

If blood sugar is not effectively controlled, diabetic nephropathy will occur in about 5 to 10 years. Diabetic nephropathy is one of the most important microvascular lesions in diabetic patients. According to statistics from the United States, Japan, and many Western European countries, diabetic nephropathy has risen to become the first cause of end-stage renal disease. At present, the incidence of diabetic nephropathy in my country is also on the rise. Due to the complex metabolic disorders and multiple organ damage in patients with diabetic nephropathy, the disease often progresses faster than other kidney diseases, and treatment is more difficult.

2. Chronic glomerulonephritis

Also known as chronic nephritis. There are many pathological types of chronic glomerulonephritis, the most common in my country are IgA nephropathy and membranous nephropathy. The clinical manifestations of chronic glomerulonephritis are diverse. Some patients have no symptoms, and some have hematuria, edema, and fatigue. It is still the primary cause of chronic kidney disease in my country.

3. Hypertension

Similar to diabetic nephropathy, if blood pressure is not effectively controlled, hypertensive nephropathy will occur in about 5-10 years. Hypertension and chronic kidney disease are causal and affect each other. With the aging of my country's population, the prevalence of hypertension is increasing year by year, and kidney disease caused by hypertension will also increase.

4. Hyperuricemia

With the improvement of people's living standards and changes in eating habits, the incidence of hyperuricemia has become more and more frequent, and people's traditional thinking ignores hyperuricemia, thinking that if uric acid is elevated without symptoms, it does not require treatment and other wrong concepts, resulting in The incidence of hyperuricemic nephropathy is also increasing.

5. Autoimmune diseases

Common autoimmune diseases that cause kidney damage include systemic lupus erythematosus, vasculitis, rheumatoid arthritis, Sjögren's syndrome, etc. These diseases are systemic damage, and the kidney is one of the most commonly affected organs.

6. Kidney damage from drugs/chemical products

The kidney is an important organ for drug metabolism. Irregularly used drugs will definitely damage the kidneys. Some drugs have direct nephrotoxicities, such as antipyretic and analgesic drugs, some Chinese herbal medicines, and chemotherapy drugs. In addition, some chemical products (such as unqualified hair dyes, skincare products, etc.), as well as industrial waste gas, wastewater, heavy metals, etc., may cause kidney damage.

7. Other reasons

Such as polycystic kidney disease, obstructive nephropathy, tumor-related nephropathy, renal damage caused by allergic purpura, virus (hepatitis B virus, hepatitis C virus), and another virus-related nephropathy.

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How to detect kidney disease early?

Regular physical examination, timely detection

The onset of some chronic kidney diseases is quite insidious, and there is often no obvious discomfort. If you don't have daily physical examinations, you can't find them early. Only with early detection, early diagnosis, and effective and standardized treatment of kidney disease can the development of the disease be well controlled. Therefore, it is recommended that people regularly test urine routine, renal function, urinary B-ultrasound (preferably once a year), and pay attention to whether there is proteinuria or hematuria, abnormal renal function, and abnormal renal structure. For patients with underlying diseases such as diabetes, hypertension, high uric acid, and kidney stones, it is recommended that the number of tests should be appropriately increased, and regular follow-up by a nephrologist should be performed.

What to do with kidney disease

1. Take it seriously and effectively control the risk factors

Active control of risk factors such as blood sugar, blood pressure, uric acid, blood lipids, and standardized treatment can control the progression of renal disease and delay the deterioration of renal function.

(1) For diabetic nephropathy, the first choice for hypoglycemic drugs is gliclaflozin, including dapagliflozin, canagliflozin, etc. It can also be combined with metformin, GLP-1 receptor agonists, and other hypoglycemic drugs to control glycated hemoglobin Below 7%, young people with diabetes should be below 6.5%, and elderly diabetics should relax blood sugar control to avoid hypoglycemia events;

(2) It is recommended to control blood pressure below 130/80mmHg; the latest KIDIGO guidelines recommend that systolic blood pressure in patients with chronic kidney disease should be controlled below 120mmHg;

(3) For patients with hyperuricemia, it is recommended that blood uric acid be controlled below 360umol/L, and for patients with gouty arthritis, blood uric acid should be controlled below 300umol/L;

(4) Low-density lipoprotein is recommended as the primary target of lipid-lowering therapy. For patients with high cardiovascular risk, low-density lipoprotein should be <2.6mmol/L, and for patients with very high cardiovascular risk, low-density lipoprotein should be <1.8mmol/L.

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2. Healthy diet, reasonable exercise, weight control

Balanced food intake, reduce the intake of seafood and animal offal, and try to avoid salty and oily food. You should have enough rest and sleep every day, and maintain proper exercises, such as walking and jogging. Try to maintain standard body weight and avoid being overweight.

3. Not taking over-the-counter drugs

Take your medicines as directed by your doctor, and never stop taking your medicines or take over-the-counter medicines by yourself. Don't trust the so-called "home remedies" and "special medicines" introduced by others. Pay attention to monitoring renal function after treatment.

4. If proteinuria and hematuria are found, it is necessary to clarify the cause

Clinically, the etiology cannot be determined solely by proteinuria or hematuria. Different types of kidney diseases have different treatment methods and prognoses. It is necessary to combine symptoms, medical history, and examination results. When necessary, renal biopsy is required to determine the pathological type.

5. Cistanche can effectively relieve the symptoms of chronic kidney disease

Cistanche deserticola, known as "desert ginseng", has high medicinal value and is a traditional precious Chinese herbal medicine in my country. Because it nourishes yang without hurting yin, it is a very good nourishing food, and it is also used in the prescriptions of nourishing the kidney and strengthening yang in the past dynasties. One of the most frequently used supplements.

Cistanche cistanche contains a large number of amino acids, cystine, vitamins, and minerals with rare nutritional and nourishing ingredients, which have a great tonic effect on male kidneys, testes, penis, cavernous body, and other sexual organs.

Cistanche Cistanche is mainly used to invigorate kidney yang, nourish essence and blood, moisten the intestines, control impotence due to deficiency of kidney yang and deficiency of essence and blood, regulate endocrine, enhance immunity, prevent senile dementia, protect the liver, resist fatigue, strengthen physical fitness, and dry intestines. Constipation, etc. 1. Use to treat deficiency of kidney yang, nocturnal emission, and slippery essence. It is often combined with medicines that warm the kidney and help yang and warm the essence and blood. 2. Treat women with deficiency of Chong and Ren, less menstrual flow, amenorrhea, and cold palace. It is often used in combination with medicines that warm Xiayuan and nourish essence and blood. 4. It can also cure intestinal dryness and constipation caused by old age and chronic illness and postpartum genital injury.

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