Sexual function decline-such as decreased libido, erectile difficulty, premature ejaculation, nocturnal emission, or "slipping essence" (in TCM terms)-often appears together with fatigue, cold limbs, frequent urination at night, and soreness in the lower back and knees. In Traditional Chinese Medicine (TCM), these patterns are commonly associated with Kidney Yang deficiency, impaired "Gate of Vitality" (命门, Mingmen) function, and weakened ability to consolidate essence.

Modern medicine may offer short-term solutions (e.g., PDE5 inhibitors or hormone-related therapies), but some individuals seek natural botanical approaches for longer-term regulation, improved constitution, and holistic support. This article presents a traditional multi-herb formula focused on "tonifying Kidney, strengthening Yang, and astringing essence"-and explains how it is prepared into an oral liquid dosage form for internal use.

 

1) Invention Title

Traditional Chinese Herbal Composition for Tonifying Kidney and Astringing Essence, and Its Preparation Method

 

 

 

2) Abstract (Translated)

This invention discloses a traditional Chinese herbal composition for tonifying Kidney and astringing essence, as well as a preparation method. It belongs to the technical field of traditional Chinese medicine.

The formula is prepared from the following raw materials in parts by weight:

Cistanche (Rou Cong Rong) 50–150 parts

Morinda officinalis (Ba Ji Tian) 50–100 parts

Cynomorium (Suo Yang) 75–150 parts

Prepared Rehmannia root (Shu Di Huang) 50–150 parts

Mantis egg-case (Sang Piao Xiao) 20–50 parts

Cuttlefish bone (Hai Piao Xiao) 20–75 parts

Alpinia oxyphylla fruit (Yi Zhi Ren) 30–75 parts

Psoralea fruit (Bu Gu Zhi) 25–75 parts

Achyranthes root (Niu Xi) 50–75 parts

Scolopendra (Wu Gong) 25–75 parts

Cornus fruit pulp (Shan Zhu Yu) 50–100 parts

Anemarrhena rhizome (Zhi Mu) 10–50 parts

Phellodendron bark (Guan Huang Bai) 20–75 parts

Pseudostellaria root (Tai Zi Shen) 20–75 parts

Preparation method: Combine all raw materials, soak in water, decoct, filter and combine filtrates, concentrate under reduced pressure, add ethanol and let stand, collect the supernatant, recover ethanol to obtain refined medicinal liquid, add sucrose, sodium benzoate, and ethyl paraben, then add purified water, mix evenly, and fill into containers to obtain the final product.

This formula has the effects of strengthening Yang and astringing essence, strongly tonifying Mingmen, mainly used for:

Erectile dysfunction, premature ejaculation, nocturnal emission or spermatorrhea due to Kidney Yang deficiency

Sexual function decline and low libido in middle-aged and elderly individuals associated with insufficient Yang-Qi.

3) Claims (Key Points, Translated & Organized)

Claim 1 - Composition

A herbal composition for tonifying Kidney and astringing essence, made from the 14 ingredients above in the listed weight ranges.

Claim 2 - One specific ratio example

A specific formula ratio (parts by weight):

Cistanche 50

Morinda 100

Cynomorium 75

Prepared Rehmannia 150

Mantis egg-case 50

Cuttlefish bone 75

Alpinia fruit 75

Psoralea fruit 75

Achyranthes root 50

Scolopendra 25

Cornus pulp 50

Anemarrhena 50

Phellodendron 75

Pseudostellaria 75

Claim 3 - Dosage form

The composition is prepared into an oral liquid for internal administration.

Claim 4 - Preparation method (Steps)

Using the above herbs as raw materials:

Soaking: Combine herbs; add water at 8–10× total herb weight; soak.

Decoction: Heat and decoct multiple times; filter; combine filtrates.

Vacuum concentration: Concentrate to relative density 1.10–1.15 (measured at 80°C).

Ethanol precipitation: Add ethanol to reach 60%–70% alcohol content; mix; stand.

Recover ethanol: Take supernatant; remove ethanol until no alcohol odor; obtain refined medicinal liquid.

Add excipients: Add sucrose, sodium benzoate, ethyl paraben; heat to dissolve; filter.

Make up volume: Add purified water to final volume; mix; fill; sterilize; finished product.

Claims 5–9 - Process details

Soak 30–60 min

Decoction twice: 1st 2 h, 2nd 1.5 h

Stand after adding ethanol: 12 h for impurity precipitation

Excipients ratio example: sucrose 100, sodium benzoate 1, ethyl paraben 0.3

Final total volume adjusted to 1000 parts

4) Technical Field & Background (Translated with Reader-Friendly Context)

Technical field

The invention relates to TCM technology, specifically a medicinal composition for "tonifying Kidney and astringing essence."

Background

In TCM, Kidney Yang deficiency is common in andrology and urology patterns, often seen in middle-aged and elderly men or in chronic conditions. Typical symptoms include:

erectile difficulty / impotence

premature ejaculation

nocturnal emission / spermatorrhea

reduced sexual function and libido

soreness in waist and knees

cold limbs and fear of cold

Conventional therapies may include PDE5 inhibitors (e.g., sildenafil), testosterone-related therapy, or antidepressants. While effective for some, issues may include side effects, recurrence after stopping medication, or intolerance in certain patients.

Existing TCM patent medicines (e.g., Jin Gui Shen Qi Wan, You Gui Wan, Wu Zi Yan Zong Wan) may help, but can have limitations:

slower onset for urgent needs

some formulas are warming and drying, possibly causing "heat" signs with long-term use

insufficient astringent strength for frequent emission / leakage patterns

lack of a comprehensive approach that both tonifies and astringes while supporting Qi and Blood

Therefore, developing an advanced compound formula with clear effects and suitable dosage form is considered valuable.

5) Core Formula Logic (Mechanism in TCM Terms)

This formula centers on:
"Warm and tonify Kidney Yang + astringe essence and stop leakage + balance Yin and Yang", with additional support for channels/collaterals.

(1) Strongly tonify Mingmen (Chief herbs)

Cistanche, Morinda, Cynomorium, Prepared Rehmannia

Warm-tonify Kidney Yang, nourish essence and blood

Cistanche / Cynomorium also support bowel movement in TCM terms, aiming for "tonify without excessive dryness"

Prepared Rehmannia nourishes Yin/blood and replenishes marrow-helping Yin-Yang mutual support

(2) Astringe essence and consolidate (Deputy herbs)

Mantis egg-case, Cuttlefish bone, Alpinia fruit, Psoralea fruit

Focus on consolidating essence, reducing leakage, supporting urinary control and reproductive stability

Targets the key complaints such as premature ejaculation, nocturnal emission, spermatorrhea

(3) Strengthen sinews and unblock channels (Assistant herbs)

Achyranthes root, Scolopendra, Cornus

Achyranthes guides downward, strengthens tendons/bones

Scolopendra is described as strongly mobile and channel-opening (TCM "insect medicine")

Cornus tonifies Liver/Kidney and astringes

(4) Harmonize and prevent excessive "heat" (Envoy herbs)

Anemarrhena + Phellodendron: clear deficiency heat / constrain excessive warming

Pseudostellaria: supports Qi and Spleen, helping absorption and overall tolerance

 

6) Why an Oral Liquid? (Practical Reading for Consumers)

Compared with pills or capsules, an oral liquid can be presented as:

faster absorption and convenience for some users

easier dose adjustment (e.g., 10–20 mL per serving)

more suitable for individuals who dislike swallowing pills

(Real-world onset varies by individual constitution, lifestyle, baseline health, and compliance.)

 

7) Example Formulations (From the Text)

The document provides multiple implementations (Examples 1–5), all within the same ingredient set but different ratios. For instance, Example 1 uses:

Cistanche 50

Morinda 100

Cynomorium 75

Prepared Rehmannia 150

Mantis egg-case 50

Cuttlefish bone 75

Alpinia 75

Psoralea 75

Achyranthes 50

Scolopendra 25

Cornus 50

Anemarrhena 50

Phellodendron 75

Pseudostellaria 75

And the process includes:

10× water soak 60 min

decoct twice (2 h + 1.5 h)

concentrate to density 1.10–1.15 (80°C)

70% ethanol precipitation 12 h

remove ethanol

add excipients

adjust to volume 1000 parts

sterilize at 105°C steam for 30 min

 

8) Reported Clinical Observation Section (As Provided; Reader Caution)

The text describes an observation (Jan–Dec 2025) with 120 male patients aged 25–65, randomized into two groups:

control group: Jin Gui Shen Qi Wan (concentrated pills)

observation group: the oral liquid prepared from this formula (dose adjusted according to different examples)

Usage described:

3 times daily, 10–20 mL each time

course: 4 weeks

outcome criteria based on symptom score reduction

Several representative cases are also described (improvements in IIEF-5 scores, nocturia, libido, etc.).

Important note for blog readers: This section is presented as written in the source text. In consumer-facing content, it's best to:

avoid overstating "cure" claims

emphasize that results vary and depend on proper diagnosis (pattern differentiation)

encourage medical guidance, especially for post-surgery patients or those with cardiovascular risk

 

9) Who Might Consider This Kind of Botanical Approach? (Educational, Not Diagnostic)

From a TCM pattern perspective, it may be relevant to individuals who have:

decreased libido + fatigue

cold limbs, fear of cold

frequent nighttime urination

lower back/knee soreness

premature ejaculation, nocturnal emissions, spermatorrhea

symptoms consistent with Kidney Yang weakness / essence instability

If symptoms include severe chest pain, fainting, blood in urine/semen, or rapid unexplained weight loss, seek medical evaluation first.

10) Safety & Compliance Notes (Recommended for Any International Blog)

For a compliant herb-industry blog (especially if you sell ingredients/extracts internationally), consider adding:

Not intended to diagnose, treat, cure, or prevent disease (where applicable)

consult a healthcare professional if:

you take anticoagulants, antihypertensives, antidepressants, PDE5 inhibitors, or hormone therapy

you have liver/kidney disease, cardiovascular disease

you are post-operative (e.g., prostate surgery)

avoid use during pregnancy/breastfeeding unless supervised (general precaution)