Focus On Chronic Kidney Disease in Children

As a pediatric nephrology doctor, I often pay attention to articles on children's kidney disease on the we-media platform. What impressed me most was this article, which described the various sufferings of the parents of an 11-year-old boy suffering from uremia. The article focused on "junk food and carbonated drinks are the main culprits of uremia" and popularized uremia to the public. There is nothing wrong with reminding people to eat healthily, but such articles can easily mislead the public and neglect the disease itself. We always think, uremia, kidney is not good, is the old people will get the disease, young, how can have uremia? Is it a problem of diet and lifestyle? Some parents also feel that children's "kidney problems" will get better as their children grow up, these are actually misunderstandings.

Click to Cistanche for kidney disease

● Children will have bad kidneys!!! Children can also get kidney diseases, such as urinary system infection, nephrotic syndrome, acute glomerulonephritis, purpura nephritis, lupus nephritis, reflux kidney disease, and so on are related to the kidney and may damage the kidney. Some kidney diseases can be cured, others require long-term follow-up; Some, if not treated in time, will cause damage to kidney function and even enter the uremia stage. Here we mainly talk about chronic kidney disease, chronic kidney disease (CKD) is caused by different causes of chronic persistent kidney damage. Renal excretion and endocrine metabolism function is seriously damaged, resulting in the retention of nitrogen-containing waste in the body, resulting in water and electrolyte, acid-base balance disorders, endocrine metabolism disorders and a series of complications. There is an irreversible decline in kidney function, which can progress to end-stage renal disease, which is uremia. The incidence of CKD in children is on the rise. According to the research data of the Nephrology Group of the Pediatric Branch of the Chinese Medical Association in 2004, the prevalence rate of kidney disease in children aged 2 to 14 years in China is 0.85%, and the proportion of uremia children in urinary system diseases is increasing year by year, which increased by 4.3 times in 2002 compared with 1990. Therefore, I would say that chronic kidney disease and even uremia in children are not uncommon!

● What causes children's kidneys is not good? So, what is the cause of chronic kidney disease in children? Does it have anything to do with diet?

In fact, improper diet is by no means the main cause of chronic kidney disease in children, the main causes of chronic kidney disease in adults is hypertension and diabetes, and the cause of chronic kidney disease in children is very different from that of adults, the main cause of children is congenital kidney and urinary tract malformation and glomerular disease. The former refers to some congenital developmental malformations of the kidney and urinary tract, while the latter includes primary and secondary glomerular diseases. The former, such as congenital hydronephrosis, renal dysplasia, vesicoureteral reflux, etc., while the latter, including refractory nephrotic syndrome, lupus nephritis, IgA nephropathy, ANCA-associated vasculitis, hemolytic uremic syndrome, etc., may cause chronic kidney disease. With the development of molecular biology, more hereditary kidney diseases have been found. Many children are often ignored in the early stage of the disease, and some of the children, in fact, if it is found early after treatment can delay or even prevent the progress of the disease, even if some congenital problems can not be cured, but also after appropriate treatment, reduce the occurrence of many complications, improve the quality of life of children.

● What are the children's situations that need to be vigilant about chronic kidney disease? The kidneys have a very strong compensatory function, and only one healthy kidney can function normally. Some manifestations of kidney disease are nonspecific and easy to be ignored. In life, if parents find that children have abnormalities in urination, including reduced urine volume, increased nocturnal urination, and abnormal urine color, such as redness, brown urine, or foam urine, this may indicate the occurrence of kidney disease, foam urine is often accompanied by eyelid or lower limb edema. Clinically, when we met children, there have been several times of naked blood urine, that is, red urine, and parents found it relatively late.

However, it should be pointed out that some problems may not be visible to the naked eye, so we recommend that children can have regular urine routine checks, a simple urine routine may be able to find some problems. In recent years, after urine screening was carried out in Shanghai, some children's "kidney problems" could be detected early, avoiding further progress. There is also a urinary ultrasound, which can also find some urinary problems. Chronic kidney disease may also show some atypical symptoms, such as poor appetite, weight loss, fatigue, also need to be noticed by parents. Some children with chronic kidney disease see a doctor because of anemia, fatigue, dizziness, pale and other symptoms; Some children with chronic kidney disease even see a doctor only because of their short stature; Other symptoms include increased blood pressure. When children go to the doctor, they often neglect to measure their blood pressure. If you have headaches, dizziness and other symptoms, pay attention to blood pressure measurement. In addition, if there is a history of kidney disease in the family and urinary abnormalities during childbirth, it is necessary to be vigilant about the occurrence of kidney disease. Although diet is not the main cause of kidney disease in children, children with kidney disease themselves need to pay attention to diet, unreasonable diet will increase the burden on the kidney, leading to complications!

● How to protect the kidney and prevent kidney disease? First of all, we should maintain good living habits, reasonable diet, proper exercise, healthy drinking water, and enhance physical fitness; Usually avoid infection, careful use of kidney damage drugs. When there are abnormal conditions, such as abnormal urination (such as increased nocturnal urination, decreased urine volume, etc.), abnormal urine color, foaming urine, and unexplained eyelid or lower limb edema, you should see a doctor in time. A family history of kidney disease is especially important. After visiting the doctor in time, relevant examinations should be done according to the doctor's suggestions, and urine routine, urine protein quantification, kidney function, B-ultrasonography of urinary system should be improved if necessary. In addition, it is also necessary to pay attention to avoid infection, repeated infection, especially infection of the urinary system may cause kidney damage. Even children, also need to regularly check urine routine, kidney function, urinary system B ultrasonography, for children, physical examination can not be ignored.

Finally, it should be pointed out that "uremia" is not "the end of the world", and through reasonable treatment, you can still obtain the continuation of life and a good quality of life. During our follow-up, some children with uremia returned to society and lived, worked and studied like others. Therefore, it is necessary to maintain a good attitude and actively face the disease.

How Does Cistanche Treat Kidney Disease?

Cistanche is a traditional Chinese herbal medicine used for centuries to treat various health conditions, including kidney disease. It is derived from the dried stems of Cistanche deserticola, a plant native to the deserts of China and Mongolia. The main active components of cistanche are phenylethanoid glycosides, echinacoside, and acteoside, which have been found to have beneficial effects on kidney health.

Kidney disease, also known as renal disease, refers to a condition in which the kidneys are not functioning properly. This can result in a buildup of waste products and toxins in the body, leading to various symptoms and complications. Cistanche may help treat kidney disease ase through several mechanisms.

Firstly, cistanche has been found to have diuretic properties, meaning it can increase urine production and help eliminate waste products from the body. This can help relieve the burden on the kidneys and prevent the buildup of toxins. By promoting diuresis, cistanche may also help Reduce high blood pressure, a common complication of kidney disease.

Moreover, cistanche has been shown to have antioxidant effects. Oxidative stress, caused by an imbalance between the production of free radicals and the body's antioxidant defenses, plays a key role in the progression of kidney disease. ies help neutralize free radicals and reduce Oxidative stress, thereby protecting the kidneys from damage. The phenylethanoid glycosides found in cistanche have been particularly effective in scavenging free radicals and inhibiting lipid peroxidation.

Additionally, cistanche has been found to have anti-inflammatory effects. Inflammation is another key factor in the development and progression of kidney disease. Cistanche's anti-inflammatory properties help reduce the production of pro-inflammatory cytokines and inhibit the activation of inflammation mandatory pathways, thus alleviating inflammation in the kidneys.

Furthermore, cistanche has been shown to have immunomodulatory effects. In kidney disease, the immune system can be dysregulated, leading to excessive inflammation and tissue damage. Cistanche helps regulate the immune response by modulating the production and activity of immune cells, such as T cells and macrophages. This immune regulation helps reduce inflammation and prevent further damage to the kidneys.

Moreover, cistanche has been found to improve renal function by promoting the regeneration of renal tubes with cells. Renal tubular epithelial cells play a crucial role in the filtration and reabsorption of waste products and electrolytes. In kidney disease, these cells can be damaged, leading to damaged renal function. Cistanche's ability to promote the regeneration of these cells helps restore proper renal function and improve overall kidney health.

In addition to these direct effects on the kidneys, cistanche has been found to have beneficial effects on other organs and systems in the body. This holistic approach to health is particularly important in kidney disease, as the condition often affects multiple organs and systems. che has been shown to have protective effects on the liver, heart, and blood vessels, which are commonly affected by kidney disease. By promoting the health of these organs, cistanche helps improve overall kidney function and prevent further complications.

In conclusion, cistanche is a traditional Chinese herbal medicine used for centuries to treat kidney disease. Its active components have diuretic, antioxidant, anti-inflammatory, immunomodulatory, and regenerative effects, which help improve renal function and protect the kidneys from further damage. , cistanche has beneficial effects on other organs and systems, making it a holistic approach to treating kidney disease.