How Is Chronic Glomerulonephritis Diagnosed?

Jun 23, 2022

Many kidney diseases have certain similarities. For example, most kidney diseases will affect the patient’s urination, such as hematuria or proteinuria. If you want to make a good diagnosis, it is better to go to the hospital for a general examination. It is also possible to judge what kind of kidney disease you have based on your external performance.


Secondary glomerular diseases such as lupus nephritis, allergic purpura nephritis, diabetic nephropathy, etc., are generally not difficult to identify based on the corresponding system manifestations and specific laboratory tests.

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Alport syndrome often begins in adolescents, and the patient has an abnormal eye (globular lens, etc.), ear (neural deafness), kidney (hematuria, mild to moderate proteinuria, and progressive renal impairment), and has a positive family history (mostly sex-linked dominant inheritance).


Another primary glomerulopathy is symptomatic hematuria, and/or proteinuria (occult glomerulonephritis: urine protein <1g/d, no edema, hypertension, and renal dysfunction.


Acute nephritis, some chronic nephritis onset is more acute, very similar to acute nephritis, but most do not have the characteristics of acute nephritis: prodromal infection 1 to 3 weeks after nephritis, transient complement C3 decline, self-healing tendency, which helps identify.


Chronic nephritis with markedly elevated blood pressure due to primary hypertensive renal damage needs to be differentiated from primary hypertension secondary to renal damage (ie, benign small arterial nephrosclerosis), which has longer-term hypertension first and then later Kidney damage, slight changes in urine (micro to mild proteinuria, microscopic hematuria and casts may be present), and another target organ (heart, brain) complications of hypertension are common.


Chronic pyelonephritis usually has a history of recurrent urinary tract infection, and abnormal imaging and renal function. There are often white blood cells in the urine sediment, and a positive urine bacteriological examination can be used to distinguish.

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From the above, it can be seen that the manifestations of nephritis have their commonalities and their characteristics. To judge the situation by yourself is to judge according to its different manifestations. Of course, if you are not 100% sure, it is recommended to take some time to go to a regular large hospital to do a professional. A health check also facilitates the doctor to prescribe the right medicine.

Can chronic nephritis be cured?

As far as the current medical conditions are concerned, many diseases can be cured, provided that the treatment is timely and the treatment method is appropriate. Chronic nephritis is a very common disease, which can be cured by timely and effective treatment in the early stage of the disease. However, if the disease develops to an advanced stage and there are serious complications, the chances of being cured are relatively small.


Experts pointed out that clinical nephritis patients always think that the pathogenesis of chronic nephritis is relatively hidden, and generally cannot make timely and effective self-diagnosis in the early stage of nephritis. However, experts pointed out that in fact, patients can judge the incidence of chronic nephritis through abnormal urine production.

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Urine abnormalities are clinically an inevitable symptom of chronic nephritis patients, and play a crucial role in diagnosing the disease, including changes in urine volume and abnormalities in microscopic examinations. Patients with edema will have decreased urine output, and the heavier the degree of edema, the more obvious the decrease in urine output. Most patients without edema have normal urine output. When the patient's kidneys are severely damaged and the concentration-dilution function of urine is impaired, there will also be an increase in nocturia and a decrease in urine-specific gravity.


At the time of clinical diagnosis, it is necessary to carry out laboratory tests on the patient's urine, which is very important for better judgment of abnormal urine symptoms. If the urine of patients with chronic nephritis is observed under a microscope, it can be found that almost all patients have proteinuria, and the content of urine protein varies from (±) to (++++). Red blood cells, white blood cells, granular casts, and hyaline casts can be seen in varying degrees in the urinary sediment. When acute attack, there may be obvious hematuria and even gross hematuria. In addition, patients with chronic nephritis will also have clinical symptoms such as dizziness, insomnia, intolerance to fatigue, and varying degrees of anemia.


In life, people should pay attention to the diagnosis of chronic nephritis through abnormal urine symptoms. Don’t ignore this typical diagnosis basis. If the condition of chronic nephritis cannot be controlled as soon as possible, then as the condition deteriorates, the renal function of patients with chronic nephritis is very easy to fail. of.

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Whether chronic nephritis can be cured or not depends on the development of the disease and its own physical condition, and it cannot be generalized. After all, different people and different diseases have different effects of treatment. In short, in order to get rid of kidney disease faster and better, it is recommended to find and treat it as soon as possible.


for more information:Ali.ma@wecistanche.com

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