The Prescription Rule About The Essence Of Chinese Herbal Tea in The Palace Of Qing Dynasty And An Preliminary Investigation On Modern Application Of Chinese Herbal Tea Ⅲ

Overview (II) Research progress on the application of TCM inheritance auxiliary platform

1. Introduction to TCM inheritance auxiliary platform (V2.5)

The TCM inheritance auxiliary platform (V2.5) (Traditional Chinese Medicine Assistance Platform, referred to as TCMISS) is a set of software jointly developed by the Institute of Chinese Materia Medica, Chinese Academy of Chinese Medical Sciences and the Institute of Automation, Chinese Academy of Sciences. This system software is based on the idea of ​​building a self-service platform for personalized needs. It is supported by methods and technologies of disciplines such as artificial intelligence, data mining, and network science. It focuses on the core needs of inheritance, development, dissemination, and innovation in clinical diagnosis and treatment and TCM inheritance. It constructs several functional modules, including a TCM diagnosis and treatment information collection module for clinical data, a knowledge management and service module for TCM ontology, and an implicit knowledge mining module for inheritance and innovation. It effectively solves the problems of non-standardization and personalization in the process of TCM inheritance. ＾
. In short, the system uses a variety of information construction technologies and methods, facing the historical accumulation, development and innovation of traditional Chinese medicine, and has built a system function of multiple modules from the accumulation of literature and prescriptions, clinical data collection to the abstraction and management of knowledge ontology, and on this basis, the explicitness of implicit knowledge, in order to achieve standardized management of many problems and difficulties in the process of traditional Chinese medicine inheritance. From the perspective of knowledge management, it has achieved multi-channel knowledge, data, and information precipitation. It has also cleaned, analyzed, summarized, and mined the stock data based on information logic, providing qualitative and quantifiable help for TCM researchers and practitioners in learning, summarizing, and researching TCM. It is hoped that this will be used as a basis to assist innovative research on TCM. It can assist the inheritance of experience of famous old TCM doctors, the summary of individual experience of doctors, the learning of young doctors, and the discovery of new drug prescriptions.

This system software takes prescription analysis as a breakthrough point, integrates data mining methods such as rule analysis, improved mutual information method, complex system entropy clustering, unsupervised entropy hierarchical clustering, etc., and can realize functions such as "data entry - data management - data query - data analysis - analysis result output - network visualization display". Prescription analysis is mainly reflected in two aspects:
One is to discover the law of medication based on the prescription data set, and the other is to use the data mining algorithm to obtain a new prescription based on the prescription data set, that is, new prescription generation. The prescription medication rules use rule analysis as a credible processing algorithm, which can determine the medication mode and medication rules according to the number of supports and confidence. The new prescription generation uses Shannon's information entropy as a measure, and at the same time, further improvements are made based on the characteristics of traditional Chinese medicine, which can determine the correlation coefficients between drugs and use clustering algorithms to finally generate new prescriptions

Traditional Chinese Medicine Cistanche That Foumous For Kidney And Sexual Health

2 Research progress on the application of traditional Chinese medicine inheritance auxiliary platform

2. 1 Summary of Experience of Contemporary National Medical Masters

The clinical literature of national medical masters is the most reliable and direct data in the study of traditional Chinese medicine inheritance. These data carry the clinical experience and significant evidence of the efficacy of national medical masters. This system software adopts the idea of ​​combining unstructured text with structured data to achieve effective management of clinical medical records of national medical masters. It can conduct in-depth and systematic analysis from the aspects of clinical diagnosis, syndrome differentiation and prescription, and medication rules, so as to assist the inheritance of the clinical experience of national medical masters. The system software was used to analyze the drug use rules of 100 famous senior Chinese medicine practitioners in the treatment of coronary heart disease and heart diseases by Deng Tietao, a master of traditional Chinese medicine; the clinical experience and drug use rules of 60 medical records of famous senior Chinese medicine practitioners in the treatment of rheumatoid arthritis, gastric diseases, etc. by Li Jiren, a master of traditional Chinese medicine; Yan Dexin, a master of traditional Chinese medicine, and Yan Zhenghua, a master of traditional Chinese medicine. " Prescriptions containing Chinese medicines such as Chuanxiong, Morus alba, Achyranthes bidentata, and Salvia miltiorrhiza, as well as Professor Yan Zhenghua's clinical medication rules for treating rheumatic arthralgia, hiccups, palpitations, chest pain, insomnia, and other diseases, and data mining, clinical experience, and experience of the national famous old Chinese medicine masters Gan Zuwang, Chao Enxiang, Lu Zhizheng, Liu Shangyi, Zhang Daning, and Guo Wei in treating chronic pharyngitis, bronchial asthma, chronic cough, hyperlipidemia, tumors, irregular menstruation, renal hematuria, urticaria, chronic eczema, liver disease, and other diseases. A systematic analysis of medication patterns.

2． 2 Analysis of the works of ancient physicians

Systematically analyzing the works of ancient physicians and then summarizing their experiences in formulating and using medications can provide an in-depth and thorough understanding of the academic thoughts, rules of medication, and characteristics of diagnosis and prescription of ancient physicians, and provide guidance for inheriting and carrying forward their academic thoughts and medication experiences. Modern clinical practice is of great significance in improving diagnosis and treatment effects. Cui Lijun and others used the Traditional Chinese Medicine Inheritance Assistance Platform (V 2.0) software to analyze the composition rules of prescriptions contained in "Tiao Bian of Febrile Diseases" to provide a reference for the inheritance of Wu Jutong's academic thoughts. The 203 first prescriptions contained in the book were analyzed to determine the frequency of occurrence of drugs in the prescriptions, and evolved to obtain commonly used drug pairs and combination rules, and 23 new prescriptions were obtained. It objectively presents Wu Jutong's prescription medication rules under the guidance of the academic thought of triple burner syndrome differentiation, and at the same time shows that the traditional Chinese medicine inheritance auxiliary platform is a valuable auxiliary tool for the research and development of traditional Chinese medicine prescriptions. Ban Yuanyuan et al. collected and organized the prescriptions contained in "Blood Syndrome Theory", and entered the names of the prescriptions and medicines into the traditional Chinese medicine inheritance auxiliary platform V

2. 5. Count the frequency of drug use, use association rules, improved mutual information method, and complex system entropy clustering to analyze drug combinations, drug correlation degrees, and drug core combinations, and use unsupervised hierarchical clustering to analyze new prescriptions. A total of 197 prescriptions were included, 423 flavors of medicines were used, and the frequency of use was a total of 2498 times. 14 new prescriptions were obtained, and the medicines used in the "Treatise on Blood Syndrome" were summarized as mainly reducing fire, regulating qi, harmonizing blood, and tonifying and purging viscera, with more cooling and moistening medicines and less hot and drying medicines. Guo Shanshan et al. 9] entered a total of 989 oral prescriptions clearly recorded in Tang Zonghai's "Treatise on Blood Syndrome", involving 231 flavors of drugs, into the traditional Chinese medicine inheritance auxiliary platform system for analysis. The top six most frequently used drugs are licorice, licorice, Angelica sinensis, ginseng, Poria cocos, raw rehmannia glutinosa, and white peony root. The core formula is licorice, angelica root, ginseng, Fu tea, raw rehmannia glutinosa, white gourd, yellow root; According to Tang Zonghai's "Blood Syndrome Treatise", oral prescriptions are flexible in use, attaching great importance to syndrome differentiation and treatment, and not purely using hemostatic drugs. The most widely used prescription drugs are to replenish qi and blood, soothe the liver and reconcile. The rules of drug use confirm his academic thoughts.