What Is The Dyskinesia in Parkinson's Patients? These Things Are Definitely Not Noticed!

Dyskinesia is a more serious type of motor complication of Parkinson's disease. It is generally more common in patients with Parkinson's disease in the middle and late stages. The reason is that after long-term use of levodopa or dopamine receptor agonists in patients with Parkinson's disease, the efficacy of the drug gradually decreases, or the dose of the drug is inappropriate. Controlled full-body dance-like movements.

The patient goes from being unable to move to the other extreme: uncontrollable movements such as sticking out tongue, crooked mouth, frowning, stomping hands and feet, turning head and waist, and even dancing all over the body, are very painful.

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Parkinson's peak dyskinesia:

Occurs in the period when the concentration of dopa in the brain is the highest, generally starting from the foot on the side with severe Parkinson's disease symptoms. Some patients have respiratory muscles and diaphragm involvement, and dyspnea occurs. The symptoms can run through the entire "open" period.

Parkinson's disease bipolar disorder:

 It is common to have abnormal involuntary movements when turning to the "on" state after taking the regular dose, and then the curative effect appears, and when turning to the "off" state, abnormal involuntary movements appear again, showing the characteristics of "hemodynamic-improvement-dysmodynamics". Sudden repetitive movements of the lower extremities are more common at first, mostly in patients with late Parkinson's disease, and often secondary to peak dyskinesia.

Parkinson's off-phase dystonia:

It mainly occurs in specific dystonic postures of feet, toes, and lower limbs, often accompanied by pain and mostly occurs in the off period. It is mainly seen in the morning before the first dose of medicine. The plasma dopa concentration is low, which may be related to the low level of dopamine receptor stimulation.

People at high risk for Parkinson's dyskinesia:

If the patient finds that he is "moving around" after taking the medicine, he should not panic, pay attention to preventing falls, and seek medical treatment in time accompanied by his family.

Before seeing a doctor, patients and their families should pay attention to the regularity of the occurrence of dyskinesia, such as how long it usually takes to appear after taking the medicine, when the effect of the medicine onset, the best time to disappear?

What should a Parkinson's patient do with Parkinson's disease "dyskinesis"?

Dyskinesias can occur when the drug is working best, or when the drug is about to stop working, which can recur several times a day. It is difficult to correct this side effect by simply relying on drug adjustment. Although reducing levodopa preparations can reduce the dance-like movements, the original Parkinson's symptoms will inevitably aggravate. Therefore, once dyskinesia occurs, clinical treatment will be very troublesome. Of course, the best way is to delay its occurrence. At present, the main early prevention strategy is to use dopamine agonists for initial treatment. According to the CALM-PD study, dopamine agonist initial treatment can delay and reduce the occurrence of dyskinesia compared with levodopa initial treatment.

Secondly, patients with Parkinson's disease must take the medication in a scientific and standardized manner, but many patients in clinical practice often ignore this problem. Some patients do not go to the hospital to have a professional doctor judge their condition and adjust the medicine, but adjust the dosage and change the medicine without authorization. Some patients hear that this medicine is effective and try it today, and add the medicine that is good. Some patients take medicines irregularly, regardless of the medication interval or dosage, as long as they are in good condition. These various wrong behaviors are also the common causes of dyskinesia in patients with Parkinson's disease.

What is the best herb for Parkinson's disease?

Cistanche extract can minimize the side effects of western medicine in the treatment of Parkinson's disease, and the drug effect is relatively more stable. By analyzing the lesions and pathology of Parkinson's disease, classifying, classifying, and staging evaluation, using "pure traditional Chinese medicine conditioning" can significantly improve the symptoms of Parkinson's such as tremor and limb stiffness, and effectively delay the time and probability of dyskinesia. 

The monomer compound campneoside II in Cistanche has obvious cytoprotective effects on cerebellar granule cell apoptosis in patients with Parkinson's disease. Tubuloside B has a good inhibitory effect on brain cell apoptosis and anti-oxidative stress in patients with Parkinson's disease. This compound is used in the treatment of Parkinson's disease.