What You Must Know About Parkinson's Disease

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Parkinson's disease (PD) is a common neurodegenerative disease, which is more common in the elderly, with an average age of onset around 60 years old. The most important pathological change in Parkinson's disease is the degeneration and death of dopamine (DA) neurons in the substantia nigra, resulting in a significant decrease in striatal DA content and causing disease. To put it another way, the fundamental cause of Parkinson’s hand tremors and leg tremors is the decrease in the number of spots in the brain caused by the reduction of dopamine in the brain. At present, the medical community does not have a correct understanding, but it is worth affirming that Parkinson’s disease The cause of the disease is closely related to age or heredity, as well as environmental factors.

What factors can cause Parkinson's disease?

1. Age. In fact, from a clinical point of view, age factors and environmental factors are the main causes of Parkinson's disease. The prevalence of Parkinson's disease will increase with age, and if you are often exposed to herbicides in daily life, mercury Trace elements such as manganese may increase the risk of developing the disease.

2. Drugs. If you regularly take certain drugs, it may also lead to an increased risk of Parkinson's disease, such as phenothiazines and butyryl phenones, as well as leisure and so on.

3. Spirit. Mental factors are also an important reason for aggravating the risk of the disease. Parkinson's patients often have depression, and long-term depression will affect a person's physical health to a large extent. Although aging is inevitable, every Individual will be getting bigger and bigger, but try to control your mood as much as possible, there are still ways to prevent it, and the treatment of Parkinson's disease also needs to start from the patient's mood. However, if Parkinson's patients occasionally have bad emotions such as tension, anxiety, or excitement, as well as fear, although it may aggravate the patient's tremor, it will not change the course of the disease. That is to say, it will not aggravate the disease. When the patient's mood stabilizes to the original state, the patient's state will return to the original state, and the tremor will return to the original level, so the patient does not need to deliberately suppress his excitement.

4. Genetics. Now the medical community believes that Parkinson's trembling of hands and feet may be caused by genetic factors, which means that Parkinson's disease has a certain genetic predisposition. People with the disease are more likely to develop the disease.

Parkinson's syndrome is particularly complex. The disease has troubled the health of many elderly friends. Once the symptoms are obvious, the patient's memory will be impaired, and there will be tremors and movement disorders. Friends should have a clear understanding of the disease and comprehensively Understand the typical manifestations of the disease, always pay attention to the health of the elderly around you, and look down to know what are the three typical manifestations of Parkinson's syndrome?

1. Tremor usually starts at the distal end of the upper limb on one side and then spreads to the lower limb on the same side and the upper and lower limbs on the opposite side, which seriously damages the health of the patient. The jaw, lips, and tongue will be affected to varying degrees. The tremor symptoms of the upper extremities were more severe than those of the lower extremities. In the early stage of the disease, the tremor only occurs when the limbs remain in a static state. When performing arbitrary movements, the symptoms of tremor can be alleviated or temporarily stopped, but when the patient is too excited, the symptoms are significantly aggravated.

2. The muscle tension of the rigid, activating, and antagonistic muscles is severely increased. When the patient's joints are passively moved, the increased muscle tension is consistent. When the patient is associated with tremors, intermittent pauses can be produced on the uniform resistance during the extension and flexion of the limb, which is more common in the elbow, wrist, neck, shoulder, and ankle joints. During the movement, the muscle rigidity is very serious.

3. Movement disorders mainly manifested as inability to exercise or reduced movement, difficulty in starting and slowing down of the patient's movement, resulting in the patient's inability to take care of themselves, especially after sitting down, unable to stand up, and unable to turn over when lying in bed. When the patient repeats the exercise, it is very easy to feel fatigued, which leads to a decline in the quality of life of the patient. Everyone must have a correct understanding of Parkinson's syndrome and treat it immediately after the onset of the body.

Parkinson's disease still has to start with prevention, because the magic medicine for Parkinson's disease has not yet come out, so you must pay attention to ensure your physical and mental health in daily life. During the treatment of Parkinson's patients, other chronic diseases, especially cerebrovascular diseases, will make the condition more complicated. Because it can make the condition worse, it becomes more and more difficult to treat.

How does Cistanche tubulosa(Schenk) R.Wight work on Parkinson's disease?

Cistanche tubulosa Extract: Echinacea, Verbasin Effective Against Parkinson's Disease

Echinacea, the functional monomer molecule in Cistanche, can reduce the increase of biliverdin reductase B caused by oxidative stress through its anti-oxidative stress effect, and protect dopaminergic neurons from oxidation Stress injury; Verbasin, the functional monomer molecule in Cistanche pins, can increase the content of DA transmitters in the brain, the number of DA neurons and the level of nigrostriatal α-synuclein protein, Protect synaptic transmission; Cistanche deserticola polysaccharide can protect nerve cells by enhancing the expression of Bel-2 and inhibiting the expression of Caspase-3, and inhibiting the apoptosis of neurons. The functional monomer molecule in Cistanche, anorthosite B, can prevent MPP-induced apoptosis and oxidative stress of the neuron, inhibit the level of intracellular reactive oxygen species, and repair neurons; Campneoside II (Vivid glycosides) Has anti-neuronal apoptosis.

To sum up, the active ingredients of Cistanche tubulosa phenylethanol total glycosides (mainly echinacoside, verbasin) can pass through the blood-brain barrier and directly act on brain cells, relieve mental stress, change health status, increase brain volume, and promote brain cells. Metabolism, thereby delaying the aging of brain cells, improving memory, maintaining long-lasting vitality of brain cells, and effectively fighting Parkinson's disease and Alzheimer's disease.