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Structural Brain Changes Associated With Overweight And Obesity Part 1

Obesity is a global health problem with a broad set of comorbidities, such as malnutrition, metabolic syndrome, diabetes, systemic hypertension, heart failure, and kidney failure. /is review descri...

Diesel Exhaust Exposure Alters The Expression Of Networks Implicated in Neuro...

The results of proteomics comparison revealed the upregulation (overrepresentation) of ACTG2 (actin, gamma 2), CAT (catalase), GSR (glutathione-disulfide reductase), GST (glutathione S-transferase)...

Diesel Exhaust Exposure Alters The Expression Of Networks Implicated in Neuro...

Protein sample preparation To prepare protein samples, the heads from 80 to 100 anesthetized larvae (5 pdf) were carefully isolated and washed with PBS before transferring to a lysis buffer which c...

Diesel Exhaust Exposure Alters The Expression Of Networks Implicated in Neuro...

Abstract Neurodegenerative diseases are a major cause of disability in the world, but their etiologies largely remain elusive. Genetic factors can only account for a minority of risk for most of th...

Microglial Adenosine Receptors: From Preconditioning To Modulating The M1/M2 ...

It is well known that the development of the nervous system requires the programmed death of a significant number of neurons [137]. Less well-known is that neuronal death is a lifelong physiologica...

Microglial Adenosine Receptors: From Preconditioning To Modulating The M1/M2 ...

3. Potential of Adenosine Receptors (AR) as Therapeutic Targets After several inconveniences in the race to obtain new drugs that act on ARs, there is evidence of excellent prospects for the approv...

Microglial Adenosine Receptors: From Preconditioning To Modulating The M1/M2 ...

Abstract: Neuronal survival depends on the glia, that is, on the astroglial and microglial support. Neurons die and microglia are activated not only in neurodegenerative diseases but also in physio...

The Effect Of Physical Exercise On Cognitive Impairment in Neurodegenerative ...

2.4. The Influence of Physical Exercise on Hormonal Activity In recent years, it has also been demonstrated that PE slows the development of neurodegenerative diseases from a hormonal point of view...

The Effect Of Physical Exercise On Cognitive Impairment in Neurodegenerative ...

Recent evidence has highlighted the importance of PE through the action of another molecule, a hormone called irisin. It was identified in 2012 in a study by Bostrom et al. [32]; irisin is generate...

The Effect Of Physical Exercise On Cognitive Impairment in Neurodegenerative ...

Abstract: Neurodegenerative diseases are a group of pathologies that cause severe disability due to motor and cognitive limitations. In particular, cognitive impairment is a growing health and soci...

Autophagy Defciency in Neurodevelopmental Disorders Part 3

FIP200 (also known as Rb1cc1) is an essential gene for autophagy induction. Guan's group previously reported that depletion of FIP200 causes a progressive loss of NSCs and impairs neuronal differen...

Autophagy Defciency in Neurodevelopmental Disorders Part 2

Complex developmental disorders WIPI2, the mammalian homolog of the yeast Atg18, is a key regulator of autophagy. WIPI2 interacts with ATG16L1 and recruits the ATG12-ATG5-ATG16L1 complex to the pha...