COVID-19 | Floating COVID-19-like HIV? A Brief Description Of The Omicron Variant
Mar 29, 2022
The new coronavirus ravaging the world discovered a new variant in November this year - Omicron. This new variant of the new coronavirus has become the focus of the world's attention since it was discovered by scientists in South Africa. For example, the state of New York in the United States immediately declared a special state of emergency based on this news. Subsequently, Japan closed the country directly because of the news. However, even so, some people think that everyone is overreacting to this new variant of the virus, while others believe that this is a precaution against this new variant of Omicron, and it is worth alerting. There is also a small number of people who believe that the virus is super infectious and immune evasion, it is an airborne spreader similar to HIV, and they are very afraid. For this reason, this article analyzes and summarizes the current research situation of this new variant virus of Omicron.
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The new variant is still characterized by a strong contagion
The biggest feature of various new coronaviruses, including the delta new coronavirus variant virus, is that it is highly infectious and has certain concealment, and may cause serious symptoms such as white lung and even death in a small number of patients. Although there is no exact data, the latest reports show that the Omicron variant is more contagious than Delta, and maybe 0.50-5 times more infectious than the traditional new coronavirus. So, how did this 0.50-5 times come about? It is generally calculated based on the R0 value of virus transmission, which represents the transmission ability of the virus. However, the current Omicron data has yet to be verified and may not be accurate. Because, in the early stage of the spread of the new coronavirus, due to limited data, some studies also gave the ultra-high R0 value of the first-generation new coronavirus, but subsequent studies corrected this error, and the R0 value was greatly reduced in subsequent studies. Therefore, it is very important to be able to quickly and accurately count the data of the infected population in Omicron, and only in this way can the R0 value be accurately calculated. Currently, the estimated data for the R0 value of Omicron may be too high.
However, it is worth reminding that the transmission results in South Africa have proved the super infectiousness of this Omicron virus. This empirical case is that various new coronaviruses are currently known to exist in South Africa, and these viruses have spread among the population. However, more than 90% of all patients with new coronavirus infections have been found to be infected with Omicron. What does this indicate? This shows that the infectious ability of Omicron is far stronger than the variant new coronavirus that has appeared before, or that it has been stronger than all the known variants of the new coronavirus.
The complex genetic background of the Covid-19 Omicron virus
The genetic background of this new variant virus of the new crown Omicron has both the characteristics of the previously famous delta variant virus and the characteristics of the new South African variant virus beta. The characteristics of the new crown delta virus are basically familiar to everyone. It is a super infectious mutant virus that has been widely spread around the world, and some people have acquired natural immunity. So, what are the characteristics of the delta virus that combines the characteristics of the new South African variant virus?
The new crown Omicron variant virus, which has extremely prominent new 32 kinds of heterozygous mutations, has mutated beyond recognition. Basically, it can be said that the virus of Omicron is already a brand new coronavirus. Moreover, it is completely different from the previous new crown virus. Why do you say that? Because, after all, the human body's ability to recognize viruses is limited. For example, a virus once known to the human body has undergone more than 30 mutations, and the human body's ability to recognize its previous ancestor virus (immunity) fails. Therefore, when the human body is exposed to the virus, the previous experience of fighting the old variant of the virus may be of no use to the new virus. In particular, the gene sequence of the new Omicron virus may partially incorporate an HIV-like ability to evade human immune surveillance.
The origin and speculation of the new crown Omicron variant virus
So, why did it arise, or where did it come from, this terrifying, new type of super virus that combines various dangerous mutations and mutation functions? Scientists are still unclear about this origin, and it is difficult to explain. For example, the virus variant of Omicron may not necessarily come directly from the country of South Africa, and South Africans may also be victims. However, scientists speculated based on Omicron's genome that the virus likely originated from an immunocompromised person or a group of patients infected with a chronic HIV virus. Because this person or group has a certain immune deficiency, the body is constantly re-infected and accumulated dozens of new coronavirus variants. These new coronaviruses have survived in the human body for a long time. On a certain day, genetic hybridization or recombination occurs, and the super virus is finally incubated. Of course, this is just a guess.
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Covid-19 Omicron's escape immune function is like HIV
It is reported that the biggest feature of the new virus of Omicron is that it can evade the immune response. In fact, the new coronavirus of the previous delta strain also has the ability to escape human immunity. So, why is Omikron's immune escape specifically mentioned?
Because, traditionally, Delta's immune escape skills are relatively weak. But this South African variant, which may have evolved in a large population of immunocompromised populations, may have absorbed the genetics of HIV, so it has a very strong immune evasion ability. The biggest problem with the Omicron variant with this ability is that it may also escape successfully for people who have been fully vaccinated, resulting in breakthrough infections that breakthrough vaccine protection. The data of the specific escape ability still needs to be revealed by further research progress.
Clinical manifestations of the Omicron virus enhance infectivity
On the one hand, it is generally believed that the main infecting groups of the new coronavirus are the elderly or those with weak constitutions, but the known clinical manifestations of the Omicron virus show that it also has strong infectivity to young people. On the other hand, the clinical manifestations of the new Omicron are very special. First of all, it has no obvious respiratory symptoms. Second, it also lacks anosmia, or anosmia, a particularly identifiable symptom. Finally, its clinical manifestations are very common and common, including headaches, muscle aches, deep fatigue, and more. We said before that the more idiosyncratic a virus behaves, the easier it is for us to catch it. Conversely, the more mundane and mundane it behaves, the harder it will be for us to catch him. Of course, this may also be one of the important reasons why the new variant virus of Omicron has spread widely and rapidly in the global population.
Conclusion
For the new coronavirus variant of the new crown Omicron, there is no special treatment in the current medical field, and everything is unknown. Based on the current known information, we can also make a guess. First of all, natural immunity can defeat the new coronavirus and various variant viruses, and Omicron will be no exception in the future. Secondly, new vaccines that are constantly developed based on mutant viruses can completely prevent virus infection, but it takes time. The update speed of vaccines usually cannot keep up with the mutation speed of the virus, which is also a common frustration.
Finally, if the infectious ability of this new virus is really as powerful as previously reported, then Omicron is indeed a new challenge that all mankind must face in 2022.
