How Cistanche Improves Kidney Function
Mar 12, 2022
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The effect of cistanche on the uterine estrogen receptors of animals with kidney function deficiency
Ling Youyu Chen Yuseng Han Singing Gu Zooming
Keywords: epimedium, cistanche, kidney function deficiency
Using oxygen-labeled thymidine(H-TdR) to participate in the specific radiation intensity of deoxyribonucleic acid (DNA) and other indicators to study the effects of Cistanche and Epimedium on the “Low kidney function” animal DNA synthesis rate formed by hydroxyl glands, The results are as follows:
cistanche treat Low kidney function
1. Materials and methods: 64 male Kunming mice weighing 25-30 grams were divided into three groups: "The Kidney function deficiency Group" (hereinafter referred to as Deficiency Group) 18 rats, fed with Hydroxy®T.5mg/0.T5ml daily; The Treatment group with Cistanche" (hereinafter referred to as Cistanche Group) 16 rats, fed with Hydroxy® 7.5mg daily /0.25ml and Epimedium and Cistanche mixture 0.5g/0.5ml; 18 rats in The Control Group group were fed 0.75ml normal saline daily for 13 days. Some animals were subjected to freezing tests, and some animals were subjected to 5H-TdR in vivo participation experiments. The improved Kay method and Marmur method were used to extract and purify DNA. The DNA content was determined by ultraviolet spectrophotometry.
2. Results
Liver and spleen DNA synthesis rate (CPM/mg; DNA/min, mean±standard error) of each group animal’s liver and spleen DNA synthesis rate (CPM/mg; DNA/min, mean ± standard error) results: Control Group (8 animals), Deficiency Group (8) and Cistanche Group (9) were 11560+1980, 5600+ 848,9900 ± 1660, respectively. It can be seen that the DNA synthesis rate of Deficiency Group is significantly reduced, and the difference is significant compared with Control Group (P<0.05): Add Epimedium After and Cistanche mixture, the DNA synthesis rate of Deficiency Group animals is significantly increased, almost reaching the normal level.
Freezing resistance experiment Put each group of animals in a metal cage at the same time and put them in a refrigerator at minus 5~61C. The freezer resistance time is: Control Group (9), "kidney function deficiency" group (10), Cistanche Group (10) were 172.5±15.5, 119.5 + 6.7, 206±12.3 (min). It can be seen that the frost resistance time of the Deficiency Group is significantly different from that of the other two groups, while the Cistanche Group has longer frost resistance than the Deficiency Group, even better than Control Group freezing time is even longer.
The observation results of the weight change and meta-mortality rate of animals in each group are: Cistanche Group and Control Group have increased weight and lower mortality rate than Deficiency Group.
effects of cistanche on kidney function
Regarding the mechanism of "kidney function deficiency" and the effects of Epimedium and Cistanche on the kidney function improvement, It is believed that the main reason is that the hydroxyl vein inhibits nucleotide reductase so that the four nucleotides are in the two Phosphorylation levels cannot be reduced to deoxynucleotide acid, resulting in a decrease in the rate of DNA synthesis, as well as disorders of protein, fat, and pansy metabolism, resulting in a series of debilitating manifestations. Epimedium and Cistanche are traditional Chinese medicines for nourishing the kidney and boosting kidney function and nourishing the marrow. Therefore, it can correct the DNA synthesis rate of "low kidney function" in animals. It may contain a biologically active factor that activates nucleotide reductase, which antagonizes the inhibitory effect of hydroxy pyridine and ensures the normal progress of nucleotide metabolism.
cistanche can treat kidney disease improve renal function
