How Does Cistanche Supplements Enhance Immune System Function?

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Cistanche plant is a famous and valuable Chinese medicine. Because of its precise curative effect and mild medicinal properties, it has been regarded as a nourishing Chinese medicine for strengthening and improving immunity since ancient times, and has the reputation of "desert ginseng". Affected by the epidemic, the function of Cistanche to enhance the immune system has attracted much attention. Cistanche polysaccharide has a significant effect on the formation and activity of human lymphocytes. It can increase the proliferation response of lymphocytes, thereby enhancing the immune function of the body.

Mechanisms of Cistanche Supplements to enhance immune system function:

Cistanche can improve imminity

1. Effect on the immune function of mice

Cistanche aqueous solution 50mg/kg or 100mg/kgig was given to mice to observe various immune function indexes. Results: The weight of spleen and thymus increased from 85 ± 12 and 37 ± 6 mg/kg to 140 ± 12 and 53 ± 6 mg/kg; the phagocytic rate of macrophages increased from 53 ± 5% to 78 ± 3%; hemolysin and hemolytic empty The plaque value increased from 147±47 and 0.05±0.1 to 361±62 and 0.18±0.01, respectively; the content of CAMP in peritoneal macrophages increased from 100±8.6pmol/ml to 152±10.9, and the content of cGMP increased from 62±12(pmol /ml) was reduced to 39±7; the lymphocyte transformation rate was increased, and the amount of 3H-TdR participating lymphocytes was increased from 178±19 (cpm) to 589±139; the delayed hypersensitivity reaction was increased from 0.54±0.15( mm) Increase the force by 0.82±0.12.

It shows that the water-soluble components of Cistanche can enhance the body fluid and cellular immunity of mice.

Improve immunity

2. Effect on the formation of human lymphocyte E rosette and acid a-naphtholase esterase (ANAE) activity:

The activity E (Ea) and total E (Et) rosette rate of normal human peripheral blood lymphocytes and drugs were measured in vitro at 37°C for 1 hour. The rosette smear was stained with ANAE. The results showed that the positive control drugs porcine thymosin F5 (500ug/ml), levamisole (10ug/ml) and astragalus at low concentration (5mg/ml), the kidney medicine Cistanche at low concentration (5mg/ml) can all increase Ea flower Knot rate, but has no effect on Et rosette rate. The high concentration of Cistanche (50mg/ml) can reduce the Et rosette rate. In the experiment, it was not found that porcine thymosin F5 and levamisole can increase the percentage of ANAE+ lymphocytes, but Cistanche deserticola can reduce the percentage of ANAE+ lymphocytes at high or low concentrations. It can be seen that the kidney medicine Cistanche can promote the formation of Ea rosettes at a certain concentration. The E rosette test is a common method to determine the number of human T cells. To a certain extent, Cistanche can reflect the body's cellular immune function.

Improve immunity

3. The effect of Cistanche on the delayed footpad response of mice:

Mice ig Chinese medicine decoction (60%, 0.5ml) for 8 consecutive days, administered d4ipSRBC challenge, 24 hours later, the footpad swelling value was measured. The results showed that the relative intensity of the footpad reaction of the Cistanche group was higher than that of the control group at 24 hours after the attack, and the Cistanche had the effect of promoting cellular immune function in the body.