Japanese Scholars Have Made Outstanding Contributions To The Scientific Research Of Cistanche Deserticola
Jun 20, 2023
The research on the chemical constituents of Cistanche deserticola began in the early 1980s. Since Kobayashi and other systematic reports on the chemical constituents of Cistanche deserticola in the desert in 1983, Japanese scholars have first done a lot of research work and made great achievements in the pharmacological research of Cistanche deserticola. Relevant papers were published as early as the first issue of the Japanese Pharmacological Journal in 1956, In 1954 and 1961, the Central Journal of Medicine also published papers on the medicinal ingredients of Cistanche deserticola.

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At the beginning of the research on Cistanche deserticola, a traditional Chinese medicine, Japanese scholars made outstanding contributions to the scientific research of Cistanche deserticola. Hiromi Kobayashi of Japan and others carried out systematic analysis and research on Cistanche deserticola produced in Mongolia, China, and successively isolated 10 Phenethyl alcohol glycosides from it. Japanese scholars also made a systematic study on the pharmacological characteristics of Cistanche deserticola. Research shows that Cistanche deserticola has the functions of regulating the Endocrine system, regulating immunity, anti-oxidation, strengthening physical strength, anti-aging, and protecting the liver. According to TCM theory, Cistanche deserticola has the effects of tonifying kidney yang, enriching blood essence, moistening intestines, and relieving constipation. Clinical indications include impotence, ejaculation, infertility, soreness and weakness in the waist and knees, uncontrollable urination due to insufficient kidney yang; Premature aging due to deficiency of essence and blood, unclear vision, thirst suppression, constipation, and amenorrhea; Collapse and leakage caused by unstable Chongren. The modern clinic is also used for the treatment of tetanus, chyle, chronic Otitis media, and other diseases. This is consistent with the efficacy of Cistanche deserticola and also confirms the other functions of chemical components in Cistanche deserticola.

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The chemical constituents of Cistanche deserticola deserticola have been studied most thoroughly in the same genus of plants, and 69 compounds have been isolated. In recent years, a large number of analytical studies on the chemical components of Cistanche deserticola have been carried out at home and abroad, and great progress has been made. Phenethyl alcohol glycosides are the main active components in Cistanche deserticola deserticola, and the research on this component is also more in-depth at home and abroad.

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In recent years, the Chinese pharmaceutical industry has also done a lot of work on Cistanche deserticola deserticola, invented the processing technology of high-quality decoction pieces and the production technology of high-content extracts, which has increased the content of Active ingredients in processed medicinal materials by 5-10 times, greatly increased the added value, and exported the extract products to the United States, Japan, and Southeast Asia. In addition, Mr. Tu Pengfei, the doctoral supervisor of Peking University, a famous Chinese pharmacologist, developed the second class new drug "total glycosides of Cistanche deserticola capsule" for anti-Alzheimer's disease and the new drug "cistanche running oral liquid" for constipation by using Phenethyl alcohol glycosides, the main component of cistanche.

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With the development of the economy, the improvement of living standards, and the aging of the social population, the research on health care and anti-aging drugs has become one of the hot areas of drug research today. With the extensive development of its pharmacological potential, its health functions have also been extensively developed. These developments of Cistanche deserticola are based on the initial scientific research achievements of Japanese scholars on Cistanche deserticola, and the outstanding contributions of Japanese scholars are indispensable.

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