Indirect protection provided by parental vaccination with mRNA Covid-19 vaccine for unvaccinated children

Contact: Audrey Hu Whatsapp/hp: 0086 13880143964 Email: audrey.hu@wecistanche.com

Since December 2019, the new coronavirus(Covid-19) has spread globally for more than 2 years, resulting in more than 370 million confirmed infections and more than 5.6 million deaths. A Covid-19 vaccine is playing a key role in fighting the spread of the pandemic. Although the current age of vaccination against Covid-19 continues to expand, there are still many children and adolescents who have not been vaccinated against Covid-19 for various reasons.

In addition to directly protecting the vaccinated individual, vaccination can indirectly protect other individuals living in the vaccinated environment. So, after the parents in the family are vaccinated against Covid-19, how does it protect the children at home?

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Recently, researchers from Israel's Clalit Institute, Harvard University, and Tel Aviv University jointly published a research paper entitled: Indirect protection of children from SARS-CoV-2 infection through parental vaccination in the journal Science.

The paper shows that parental vaccination against Covid-19 can effectively protect children at home from Covid-19. This study highlights that vaccination can protect not only individuals but their loved ones as well. It also highlighted the importance of increasing vaccination rates among vaccinated populations to curb the spread of the COVID-19 pandemic and protect those who cannot be vaccinated.

Current research shows that parental vaccination provides substantial protection to children living in the same household, emphasizing that vaccination protects not only vaccinated individuals but also their loved ones.

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The Clalit Institute, in collaboration with researchers from Harvard University and Tel Aviv University, analyzed one of the world's largest databases of comprehensive health records to examine indirect protection provided by parental vaccination with Pfizer/BNT162b2 mRNA Covid-19 vaccine for unvaccinated children at home.

Effect

Previous studies have shown that two doses of Pfizer/BNT162b2 mRNA COVID-19 vaccine had a protection rate of 94.4% in the early stage (epidemic stage of the Alpha mutant) and 86.3% in the later stage (epidemic stage of the Delta mutant).

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Between December 2020 and March 2021, a wave of Covid-19 infections dominated by Alpha mutants swept Israel. The research team studied 400,733 unvaccinated children and adolescents from 155,305 different households during this period. Comparing unvaccinated parents with parents who received two doses of the vaccine showed that two doses of the Covid-19 vaccine for one parent reduced the risk of infection in the child by 26.0%, and two doses of the Covid-19 vaccine for both parents reduced the child's infection risk. The risk of infection was reduced by 71.7%.

Between June 2021 and October 2021, a wave of Covid-19 infections dominated by Delta mutants swept Israel again. The research team studied 181,307 unvaccinated children from 76,621 different households during this period and compared parents who received a third booster dose with parents who had only received two doses of the Covid-19 vaccine at least five months earlier. compare. The results showed that one parent vaccinated with a booster shot could reduce the child's infection risk by 20.8%, and both parents had a 58.1% reduction in the child's infection risk.

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In addition, the study also showed that the indirect protective effect of parental vaccination against Covid-19 was fairly consistent across families of different sizes and children of different age groups, including those in the 0-2 and 3-6 age groups who were still unable to receive the Covid-19 vaccine child.

The study further explores the mechanism of this indirect protective effect - not only are vaccinated parents less likely to contract the virus themselves, but even if they do, they are less likely to transmit the infection to other family members.

Taken together, the results of this study suggest that parental vaccination provides substantial protection for children in the family. These results underscore the importance of increasing vaccination rates among vaccine-eligible populations to curb the spread of the COVID-19 pandemic and protect those who cannot be vaccinated.

For this study, Professor Ben Reis of Harvard Medical School said that parents have a responsibility to protect their children from harm, especially those whose children are too young to be vaccinated against the Covid-19. Clear evidence - getting vaccinated not only protects yourself but also your children.

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