Principles And Rules For Andrological Medication Based On The Axis Of Brain-heart-kidney-essence Chamber

【Abstract】The theory of the " brain-heart-kidney-essence chamber" axis,which supplements and contributes to the construction of the andrological theory system of traditional Chinese medicine,aims to summarize and grasp the laws of andrological pathogenesis and guide andrological syndrome differentiation and medication． The core concept of the axis is that the brain,heart and kidney act as a whole and play a vital role in the onset of male diseases． "Brain god" is used to embrace the environmental,social pressure,psychological and other pathogenic factors for male diseases in contemporary society． The kidney,which is directly and closely related to the onset of male diseases,is considered as the core of the syndrome differentiation system of zang-fu organs． The abuse of the essence chamber is the final link in the onset of male diseases． Based on this theory,the author outlines the characteristics of prescription selection and summarizes the combinations of common,experienced and special drugs,aiming to provide a better guidance for clinical medication in andrology．

【Key words】" brain-heart-kidney-essence chamber" axis; drug combination; andrology; medication law

 

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The "brain-heart-kidney-sperm chamber" axis theory [1] is a systematic theory of etiology, syndrome differentiation, and treatment of men's diseases based on the basic theories of traditional Chinese medicine, the characteristics of the onset of modern men's diseases, and a combination of a large number of clinical practices. It aims to summarize and grasp the laws of the onset of men's diseases, guide the syndrome differentiation and medication of men's diseases, and improve the construction of the theory of men's diseases in traditional Chinese medicine. This axis reflects the three major factors of men's diseases: environmental changes, social pressure and psychological abnormalities, visceral disorders represented by the kidney, and abnormal function of the sperm chamber. Environmental changes and abnormal psychological activities, abnormal regulation of the heart's blood vessels, heart storage and brain spirit, kidney's storage, kidney's reproduction, kidney's defecation and other functions, and sperm chamber dysfunction can all lead to the occurrence of men's diseases. Moreover, each link can affect each other and cause disease to each other, that is, the brain, heart, kidney, and sperm chamber are used for each other physiologically and affect each other pathologically, reflecting the concept of the unity of form and spirit. The onset of men's diseases is based on the "brain-heart-kidney-sperm chamber" axis, and the corresponding differentiation and treatment ideas are established at the same time. Based on this axis theory and combined with clinical practice, we sorted out the commonly used Chinese medicines, drug pairs, prescriptions, etc. in men's medicine, in order to better guide clinical practice and further enrich the content of the "brain-heart-kidney-sperm chamber" axis theory.

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1 Principles of medication along the "brain-heart-kidney-sperm chamber" axis

 

1.1 Mind-body coordination

 

Men's diseases are closely related to psychological factors. Psychological factors can not only lead to the occurrence of diseases, but also affect the prognosis, progression and outcome of diseases. The brain-heart spirit is an important part of the axis theory for this reason. In clinical practice, many diseases such as impotence, premature ejaculation, chronic prostatitis, low libido, etc., many patients are accompanied by symptoms of brain-heart spirit disorder such as anxiety, irritability, and excessive stress [2-3], and these symptoms are not conducive to the recovery of the disease. Therefore, medication emphasizes mind-body coordination [4], that is, while treating diseases or symptoms, we must fully consider mental and psychological factors, and at the same time regulate the mind and brain spirit and relieve emotions, which is conducive to the recovery of men's diseases.

 

1.2 Treating the whole and the part together

 

The whole determines the part, and the part affects the whole. Overall health is the foundation of men's health. Therefore, clinical diagnosis and treatment of male diseases should first be considered from the overall perspective, including the patient's constitution and the differentiation of yin and yang deficiency and excess, and then observe the cold, heat, exterior and interior properties of local lesions. Local lesions should be subject to overall differentiation. Medication should not only eliminate or relieve local symptoms as quickly as possible, but also consider prognosis and care from the overall perspective.

 

2 Medication rules for the "brain-heart-kidney-sperm chamber" axis

 

2.1 Regulating the mind of the heart and brain

 

2.1.1 Brain spirit is not nourished

 

The brain is the home of the soul. Modern people stay up late and work overtime for a long time, which secretly consumes the yin and blood of the brain marrow, causing the brain vessels to be not nourished [5], and the spirit is out of control. It can be seen that yawning is frequent, sexual desire is indifferent, and the opening and closing of the sperm chamber is disordered, which manifests as frequent urination, urgency, dysuria, premature ejaculation, nocturnal emission, and anejaculation. Treatment should be to nourish the brain and spirit. Commonly used drugs include: placenta, processed Polygonum multiflorum, Alpinia oxyphylla, walnut meat, jujube seed, longan meat, cypress seed, etc.; Commonly used drug combinations: Acorus calamus-Hypericum perforatum-Alpinia oxyphylla, etc., and the representative prescription is Dabuyuan decoction.

 

2. 1. 2 Mental restlessness

Sexual intercourse encounters a sudden frightening thing, or lacks self-confidence, is quite afraid of sex life, or the wife is strong and complains more, resulting in mental restlessness, erection without firmness, or premature ejaculation, or spermatorrhea, or infertility
, etc. Treatment principles include heavy tranquilization and tranquilization, brain nourishment and tranquilization, and heat-clearing and tranquilization. Commonly used drugs for heavy tranquilization and tranquilization include: dragon bone, dragon tooth, oyster, magnet, amber, etc.; brain nourishment and tranquilization commonly use jujube seed, Schisandra chinensis, Poria, cypress seed, etc.; heat-clearing and tranquilization often use lotus seed heart, Coptis chinensis, bamboo leaf, rush, etc. Commonly used drug pairs include dragon bone-oyster, lotus seed heart-schisandra chinensis, etc. Representative prescription: Guizhi plus dragon bone and oyster soup. "Jingyue Complete Book·Impotence" says: "If there is a sudden shock, the penis will become impotent, which is also the proof."

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2. 1. 3 Brain and nerve fatigue

Due to fatty and sweet food, phlegm and dampness are generated internally, resulting in obesity; or due to poor living environment and tense relationship between husband and wife, resulting in lack of sexual interest and pleasure; or due to excessive smoking and drinking and lack of exercise, phlegm and dampness are accumulated and cover the clear orifices, forming a real syndrome dominated by phlegm and dampness or a mixed syndrome of spleen deficiency and phlegm and dampness. Treatment should be to remove dampness (phlegm) and clear the brain. Commonly used drugs include: mint, calamus, costus root, French pinellia, clove, and sweet pine. Commonly used drug combinations include mint-French pinellia-clove, sweet pine-Chuanxiong-Agastache, etc. Representative prescription: Daotan Decoction. Removing dampness (phlegm) and clearing the brain is a symptomatic treatment method. It should not be used for a long time and should be stopped when the disease is severe.

 

2. 1. 4. Deficiency of heart and timidity

The gallbladder is the place of essence, responsible for decision-making and planning. If the courage is insufficient, the heart qi is often weak and the heart yang is often weak. In men's medicine, impotence, premature ejaculation, low libido, etc. can be seen. The treatment should focus on strengthening the mind and courage. Commonly used herbs include ginseng, polygala, calamus, cinnamon twig, allium macrostemon, and poria. Commonly used drug combinations include cinnamon twig-allium macrostemon-polygala, aconite-poria frankincense, ginseng-polygala-arisaema, etc. Representative prescriptions include Guxin Dan.

 

2. 1. 5 Worry and hurt the mind

Excessive mental work or unhappy life, depressed mood, and excessive thinking will hurt the brain, so the mind will not think about sex, frequent urination, urgent urination, or forced urination but not firm erection, or even premature ejaculation. The treatment should regulate emotions and open the mind. Commonly used drugs include: Hypericum perforatum, Bupleurum, Curcuma, Cyperus rotundus, rose, Chinese rose, Magnolia officinalis flower, Albizzia julibrissin, Albizzia julibrissin bark, etc.; Commonly used drug combinations include Hypericum perforatum-Curcuma-Ephedra, etc.; Representative prescriptions include: Dayu Decoction. In clinical practice, attention should be paid to regulating emotions and refreshing the mind, which will complement each other and achieve obvious results. For example, the disease of spermatorrhea has complex causes and many prescriptions. However, in clinical practice, people with worry, heart and spleen deficiency, and qi stagnation are often encountered. "Jingyue Complete Book·Spermatorrhea" says: "Some people who have excessive thinking often have nocturnal emission. This is because their qi is insufficient and their heart and spleen are weak." When encountering such patients in clinical practice, Guipi Decoction with Albizzia julibrissin bark, Albizzia julibrissin flower, Hypericum perforatum, rose, Acorus calamus, etc. can be used to treat the root cause of the disease, rather than stopping nocturnal emission and using astringent and astringent products.