The benefit of cistanche on Anti- Parkinson's and Parkinson's Disease

Contact: emily.li@wecistanche.com

Keywords: Cistanche, cistanche extract, cistanche tubulosa extract, benefits of cistanche tubulosa, Parkinson's disease, Echinacoside, Acteoside, Verbascoside

There is a lot of evidence that the extract of Cistanche tubulosa can effectively anti- Parkinson's disease, and this has to start with its ingredients. This article will take you to understand why Cistanche extract can resist Parkinson's.

Cistanche benefit: Anti- Parkinson's and Parkinson's Disease

Echinacoside (Echinacea)

The functional monomer molecule in cistanche, echinacoside, can reduce the increase of biliverdin reductase B caused by oxidative stress through its anti-oxidative stress effect, and protect dopaminergic neurons from an anti-oxidation Stress injury.

Echinacoside (Echinacea) from cistanche: Anti- Parkinson's and Parkinson's Disease

Experiments have confirmed that the extract of Cistanche Echinacea can effectively inhibit the reduction of dopaminergic neurons and dopamine transporters in the substantia nigra of PD model mice induced by MPTP (neurotoxin), and can enhance the neurotrophic factor (neurotrophic, NTF) Activity and protein expression level, reduce the ratio of mRNA and protein in apoptosis and Bax/Bcl-2.

Dopamine (C6H3(OH)2-CH2-CH2-NH2), a wonderful neurotransmitter, is the "reward center" of the brain. Dopamine, which "dominates love", can also affect a person's emotions, making you happy and making you worry. The incidence of depression in PD patients is 20-40%, and the incidence of anxiety is 24-75%.

Acteoside (Verbascoside / Verbascum glycosides)

Research and analysis have shown that the functional monomer molecule in Cistanche tubulosa extract-verbascoside can improve the behavior of C57 mice induced by MPTP, increase the content of DA transmitters in the brain, the number of DA neurons and the substantia nigra striatum α-Synapse (α-synuclein) protein level, protect the synaptic transmission;

Acteoside (Verbascoside / Verbascum glycosides) from cistanche: Anti- Parkinson's and Parkinson's Disease

Cistanche cistanche polysaccharides can inhibit neuronal apoptosis by enhancing the expression of Bel-2 and inhibiting the expression of Caspase-3, thereby protecting nerve cells.

Anthocyanin-B

Damaged and insufficient dopamine neurons will cause most PD patients to lose the ability to control their muscles. Some patients will be the first to show on the facial muscles, seldom blink their eyes, reduce the turning of their eyes, and have a dull expression, even if they intentionally make expressions. It also looked stiff, as if wearing a mask. The functional monomer molecule in the extract of Cistanche, cylindroid B, can prevent the neuronal apoptosis and oxidative stress response caused by MPP, inhibit the level of intracellular reactive oxygen species, and repair neurons; Campneoside II Glycoside) has an anti-neuronal apoptosis effect.

Cistanche is rich in a variety of amino acids, minerals, and other active ingredients needed by the human body, which can improve human immunity. By reducing the activity of DA, enhancing the activity of γ-aminobutyric acid and 5-HT, it exerts a calming effect. Improve sleep quality; the active ingredients of Cistanche Tubula can pass through the blood-brain barrier and directly act on brain cells, relieve mental stress, change health, increase brain capacity, promote brain cell metabolism, and delay brain cell aging and improve Memory, maintain the lasting vitality of brain cells.