What Are The Early Symptoms Of Uremia? Pay Attention To These Signs

Some kidney patients are surprised when they learn that they have uremia: they can eat and drink normally, and they don't feel uncomfortable. They just come to see a doctor for a cold. How come they are diagnosed with uremia?

In fact, uremia will not be "cured overnight"! Because our kidneys have very strong compensatory functions, early kidney disease generally does not have too many symptoms, so if you don't take a serious physical examination, early kidney disease is difficult to detect, which leads to many people without medical knowledge ignoring the early treatment of chronic kidney disease; of course, there are also some people who do not understand the early symptoms of uremia, and often treat some symptoms of uremia as diseases of other departments and delay treatment. So, today I will talk about the early symptoms of uremia from a professional perspective, hoping to help you!

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Most patients with uremia do not have typical symptoms in the early stage. The more common discomfort is a slight sense of fatigue, and some people begin to urinate more at night, especially in the second half of the night. This phenomenon of increased nocturia is mostly due to the fact that after the kidney function declines, the toxins produced during the day cannot be excreted, and they have to use the night to "work overtime". So sometimes increased nocturia is the earliest symptom of renal dysfunction. There are also some patients with hypertension who were originally very effective in antihypertensive treatment, but recently suddenly became inexplicably ineffective. In this case, you should also be careful that the kidney function cannot compensate and maintain the current blood pressure. Some female patients also have anemia or increased menstrual volume for unknown reasons. Be careful that there is something wrong with the kidney, because the human hematopoietic function mainly depends on the kidney's ability to secrete a kind of erythropoietin. Once the kidney function is abnormal, the secretion of this hormone will be significantly reduced.

How can we find it earlier?

I think first you have to know what the symptoms of uremia are, and then you will think in this direction.

01 Gastrointestinal symptoms

Some patients often feel nausea and vomiting when brushing their teeth in the morning. This phenomenon often does not last long and can be improved after diverting attention. In fact, nausea, vomiting, and loss of appetite are the early and most common manifestations of uremia. Don't think that nausea and vomiting are all stomach problems, and take a lot of stomach medicine orally to delay the condition.

02 Cardiovascular system lesions

Kidney disease can cause high blood pressure, and high blood pressure can also damage the kidneys. Renal hypertension is often the earliest symptom of deterioration of renal function in chronic kidney disease. Some people think that their parents have hypertension and that their own high blood pressure is a genetic phenomenon. Strictly speaking, the cause of hypertension before the age of 40 should be carefully sought, such as secondary hypertension caused by chronic nephritis and primary aldosteronism. Early detection of hypertension and early control of hypertension can not only delay the progression of kidney disease, but also prevent cardiac hypertrophy and even heart failure.

03 Symptoms of the blood system

Due to the increase in toxin levels in the body, patients with uremia may experience increased menstrual flow, nosebleeds, gum bleeding, skin ecchymoses, pale complexion, fatigue, etc.; going to the hospital for examination will reveal abnormal coagulation function, anemia, thrombocytopenia, etc.

How can anemia occur if the kidneys are not good? It turns out that the kidneys secrete a hematopoietic substance - erythropoietin. When renal function declines, the secretion of this substance will decrease, and red blood cell production will be impaired. Gradually, anemia will appear, which is called renal anemia. Generally speaking, renal anemia will occur when the glomerular filtration rate is less than 60ml/min.

04 Water and electrolyte imbalance

Early edema is mainly manifested as eyelid edema and (or) pitting edema of both lower limbs. In the late stage, body cavity effusion, i.e. pleural and abdominal effusion, chest tightness, shortness of breath or abdominal distension may occur. If edema is found and urine volume is significantly reduced, you must seek medical attention in time, and be careful of combined hyperkalemia. Severe hyperkalemia can be life-threatening. It is worth mentioning that many patients with kidney disease are using renin angiotensin inhibitors to control hypertension and proteinuria. These drugs are very likely to cause hyperkalemia. Therefore, if you experience chest tightness, fatigue, and poor diet that are difficult to explain during medication, you should pay attention to checking blood potassium.

05 Increased nocturia

Normal adults generally do not urinate at night. If you habitually get up 2-3 times or more every night, and the urine volume at night is greater than 1/3 of the total urine volume in 24 hours, there may be a problem with the kidney's concentration function. Go to the hospital to check your kidney function.

06 Skeletal system

Uremia patients often lack a hormone that regulates bones, and are prone to osteoporosis, osteomalacia or osteitis fibrosa, which manifests as generalized bone pain, such as knee pain when climbing stairs, heel pain after walking for a long time, and fractures in severe cases.

In addition, uremia covers all systems of the body, and may also have symptoms such as bad breath, itchy skin, hand and foot cramps, and sleep disorders. If you suspect you have uremia, it is actually very simple to rule out kidney disease by doing blood routine, urine routine, renal function, and bilateral kidney B-ultrasound. For high-risk patients such as diabetes, hypertension, gout, and obesity, regular physical examinations should be conducted for early intervention.

How Does Cistanche Treat Kidney Disease?

Cistanche is a traditional Chinese herbal medicine used for centuries to treat various health conditions, including kidney disease. It is derived from the dried stems of Cistanche deserticola, a plant native to the deserts of China and Mongolia. The main active components of cistanche are phenylethanoid glycosides, echinacoside, and acteoside, which have been found to have beneficial effects on kidney health.

Kidney disease, also known as renal disease, refers to a condition in which the kidneys are not functioning properly. This can result in a buildup of waste products and toxins in the body, leading to various symptoms and complications. Cistanche may help treat kidney disease ase through several mechanisms.

Firstly, cistanche has been found to have diuretic properties, meaning it can increase urine production and help eliminate waste products from the body. This can help relieve the burden on the kidneys and prevent the buildup of toxins. By promoting diuresis, cistanche may also help Reduce high blood pressure, a common complication of kidney disease.

Moreover, cistanche has been shown to have antioxidant effects. Oxidative stress, caused by an imbalance between the production of free radicals and the body's antioxidant defenses, plays a key role in the progression of kidney disease. ies help neutralize free radicals and reduce Oxidative stress, thereby protecting the kidneys from damage. The phenylethanoid glycosides found in cistanche have been particularly effective in scavenging free radicals and inhibiting lipid peroxidation.

Additionally, cistanche has been found to have anti-inflammatory effects. Inflammation is another key factor in the development and progression of kidney disease. Cistanche's anti-inflammatory properties help reduce the production of pro-inflammatory cytokines and inhibit the activation of inflammation mandatory pathways, thus alleviating inflammation in the kidneys.

Furthermore, cistanche has been shown to have immunomodulatory effects. In kidney disease, the immune system can be dysregulated, leading to excessive inflammation and tissue damage. Cistanche helps regulate the immune response by modulating the production and activity of immune cells, such as T cells and macrophages. This immune regulation helps reduce inflammation and prevent further damage to the kidneys.

Moreover, cistanche has been found to improve renal function by promoting the regeneration of renal tubes with cells. Renal tubular epithelial cells play a crucial role in the filtration and reabsorption of waste products and electrolytes. In kidney disease, these cells can be damaged, leading to damaged renal function. Cistanche's ability to promote the regeneration of these cells helps restore proper renal function and improve overall kidney health.

In addition to these direct effects on the kidneys, cistanche has been found to have beneficial effects on other organs and systems in the body. This holistic approach to health is particularly important in kidney disease, as the condition often affects multiple organs and systems. che has been shown to have protective effects on the liver, heart, and blood vessels, which are commonly affected by kidney disease. By promoting the health of these organs, cistanche helps improve overall kidney function and prevent further complications.

In conclusion, cistanche is a traditional Chinese herbal medicine used for centuries to treat kidney disease. Its active components have diuretic, antioxidant, anti-inflammatory, immunomodulatory, and regenerative effects, which help improve renal function and protect the kidneys from further damage. , cistanche has beneficial effects on other organs and systems, making it a holistic approach to treating kidney disease.