What Is Renal Failure?

Contact: emily.li@wecistanche.com

Renal failure is a common serious disease, and there is currently no cure. There are many factors that cause the failure of human kidney function, not only related to its own factors but also related to various external factors. No matter what kind of chronic kidney disease, it may eventually lead to renal failure. Next, let's take a closer look at kidney failure.

Cistanche can treat renal insufficiency

1. What is renal failure?

Renal failure is caused by various kidney diseases that cause severe damage to the nephrons, resulting in the decline of the body's kidney regulatory function and the decline of renal excretion. If the patient suffers from renal failure, it will cause the patient's renal function to decline over time, making the filtration capacity of the kidney less than about 30% of the ordinary kidney. With the further development of kidney disease, patients will also experience severe renal insufficiency, which will eventually evolve into end-stage renal failure, which threatens the life of the patient. Finally, the patient can only rely on dialysis for treatment.

2. What are the types of renal failure?

Renal failure is divided into two types: first, acute renal failure; second, chronic renal failure. Acute renal failure develops faster, and it is generally caused by three reasons: one is that the kidney is damaged by poisons; the other is that the kidney is blocked by some factor and its function is impaired; and the third is that Insufficient blood supply to the kidneys, such as burns and trauma. But chronic renal failure is the opposite. This disease is caused by the long-term disease of the kidney, and with the development of the disease and condition, the kidney function is weakened, and the phenomenon of kidney failure occurs.

Renal failure is a pathological condition in which partial or total loss of kidney function

3. Symptoms of renal failure

The body begins to show edema: Once the patient has renal failure, there will often be edema in the lower limbs. Many people think that this is caused by standing for a long time and that this is a symptom of high blood pressure. For renal failure, there will be no obvious symptoms at first, and only after some stimulation can it show some symptoms.

Skin problems: When a patient with renal failure develops, the patient’s skin will become drier and drier, and even scaly will appear. This is because the patient has started to suffer from water shortage, which not only damages the patient’s skin, but also It will also have a great impact on the appearance of the patient, and bring many adverse effects on the life and work of the patient.

Back pain: If a patient has kidney problems, it will first be reflected in the patient's waist, and the patient will have symptoms of back pain. However, many patients believe that waist pain is caused by other factors, leading to misdiagnosis. Once the patient has severe symptoms of renal failure, he will have severe low back pain. In the face of this situation, we need to take a targeted approach to deal with it.

Frequent wake-ups: If patients drink too much water before going to bed, they will get up frequently. For ordinary people, usually wake up about two or three times a night. If the patient wakes up more often Then, it is possible that the kidneys are abnormal, and the patient wakes up more often, which also shows that the symptoms of renal failure are more serious.

Inability to concentrate: For patients, when kidney function is healthy, part of urea will be excreted after kidney metabolism. Once the patient’s kidney function fails, these toxic substances will accumulate in the patient’s body, which It can cause dizziness and lack of concentration in the patient. After a long time, the patient will suffer from uremia, which will cause more damage to the patient's body.

4. What are the clinical manifestations?

(1) Oliguria period. This period is a critically ill stage. Patients may experience oliguria (i.e. daily urinary output less than 400mL) or anuria (i.e. daily urine output less than 100mL), tubular urine, proteinuria, hematuria, and high urine sodium. Some patients are more severely ill, such as water intoxication, hyperkalemia, metabolic acidosis, azotemia, etc., which may be life-threatening, and hyperkalemia usually causes death. This period lasts for a few days or weeks. The longer the duration, the worse the patient’s prognosis will be.

(2) Polyuria. After the oliguria period, the patient's urination volume will gradually increase. When the daily urination volume reaches more than 500mL, it means that the patient has entered the polyuria phase. The patient's urine output will then show a daily increase in multiples. At the peak, the patient's daily urine output can reach 3000-6000mL, and even some patients' urine output will reach more than 10000mL. When the patient just enters the polyuria period, although the urinary output is increasing, the clearance rate of the kidney is still low, and the residual metabolites in the body still exist. After about 4 to 5 days, with the increase in urine output, the patient's creatinine and serum urea nitrogen will gradually decrease, and the symptoms of uremia will be significantly improved. Due to a large amount of urine, electrolytes such as sodium and potassium will be excreted in the urine, which may cause dehydration or electrolyte disturbance in the patient. Pay attention to this period. The duration of this period is about 1 to 2 weeks.

(3) Recovery period. During this period, the patient's urine output is slowly returning to normal. After 3-12 months, the patient's renal function will slowly recover. Most patients' renal function levels can return to normal, but there are also a small number of patients with chronic renal failure.

Some patients with end-stage renal failure can consider kidney transplantation

5. Which kidney diseases can cause renal failure?

(1) Inherited nephropathy, such as Alport syndrome, polycystic kidney disease, etc.

(2) Obstructive nephropathy, such as prostatic hypertrophy, tumors, urinary tract stones, etc. are all factors that cause urinary tract obstruction.

(3) Interstitial tubule diseases: gout, food poisoning and drug poisoning (such as heavy metal toxic nephropathy, analgesic nephropathy, aristolochic acid nephropathy), infectious nephropathy (renal tuberculosis, chronic pyelonephritis).

(4) Renal vascular diseases, such as renal arteriosclerosis, hypertension, etc.

(5) Secondary glomerulonephritis: amyloid nephropathy, diabetic nephropathy, multiple myeloma, vasculitis, kidney damage, lupus nephritis, etc.

(6) Primary glomerulonephritis: chronic glomerulonephritis, such as mesangial proliferative glomerulonephritis, focal segmental sclerosing glomerulonephritis, membranous proliferative glomerulonephritis, IgA nephropathy, etc. .

Early prevention is the key to preventing renal failure

Early renal failure is the best time to prevent. This is because in the early stage of renal failure, its clinical symptoms are relatively mild. Doing a good job in the prevention of renal failure at the early stage can reduce the appearance of aggravation of the disease, such as Patients with refractory nephropathy, hypertension, diabetes, etc., actively cooperate with treatment in the early stage, which can effectively prevent the occurrence of chronic renal failure.