​What To Do With Constipation And Parkinson's Disease-associated Constipation, Here Is The Complete Answer For You~

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Parkinson's disease is a degenerative disease of the senile nervous system with motor symptoms such as bradykinesia, rigidity, and resting tremor as the main clinical manifestations. symptom. Constipation can occur before the motor symptoms of Parkinson's disease appear, or it can accompany Parkinson's disease for many years, which has a great impact on the quality of daily life of patients with Parkinson's disease.

Constipation may be the most common manifestation of gastrointestinal dysfunction in Parkinson's disease, with an incidence of more than 50% in Parkinson's disease patients, about 2-4 times that of normal people. Numerous studies have shown that constipation may occur 10-20 years before clinical diagnosis in men with Parkinson's disease, with inconsistent results in women.

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So what exactly are the symptoms of constipation in Parkinson's patients?

PD constipation symptoms are mainly manifested as decreased defecation frequency (less than 2-3 defecations in a week), defecation time greater than 30 minutes, low and dry stool volume, laborious defecation, feeling of incomplete or obstructive defecation, and chronic laxative dependence, Abdominal pain, etc.

Which type of Parkinson's disease patients is prone to constipation?

Generally, patients with older age, longer duration of Parkinson's disease, high drug dose, severe motor symptoms, depression, anxiety, and less exercise are more prone to constipation.

Will the anti-Parkinsonian medication I am taking now affect constipation?

Among the anti-Parkinson's disease drugs, the anticholinergic drugsantan and levodopa have the greatest effect on gastrointestinal motility. Antan, in particular, has a definite side effect of constipation. L-dopa can aggravate constipation by inhibiting gastrointestinal motility by slowing the movement of the gastrointestinal tract. However, there are also studies that levodopa can improve rectal contraction function and relieve constipation symptoms in PD patients. Therefore, in addition to Antan, the effects of other anti-Parkinson's disease drugs on constipation vary from person to person.

What is the cause of constipation?

There are many reasons for constipation. In addition to the primary disease of the body, bad eating habits, bad bowel habits, mental and psychological factors can all cause constipation.

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How to treat constipation?

• 1. Adjust the diet structure: increase the intake of cellulose and water in the diet, ensure the daily intake of cellulose (30g/d), the amount of water (1.5-2L), and oils and nuts can help prevent constipation.

  Cereals, potatoes, and beans are all fiber-rich foods. Eat more whole grains (brown rice, black rice, corn, beans, sweet potatoes, etc.), vegetables (various green leafy and stem vegetables such as celery, spinach, Chinese cabbage), fruits, which can improve constipation symptoms. These foods are rich in fiber, which can promote bowel movements and relieve constipation. At the same time, it is necessary to drink more water. Fiber and water together keep our intestines working properly. Each fiber is like a small sponge. Only after fully absorbing water and expanding can it increase the volume of feces and make the feces soft and easy to discharge. . Without moisture, fibroblasts will remain dry and tough, in fact, it will only aggravate constipation. Therefore, it is necessary to ensure sufficient water intake every day.

  And high-calorie, high-fat foods (such as fried foods, spicy foods, fatty meat, butter, pickled foods) are not easy to digest, try not to eat them.

  In addition, friends with constipation can insist on eating Cistanche or its products for a long time, because Cistanche contains a lot of galactitol and oligosaccharides, which can effectively promote gastrointestinal motility, increase intestinal osmotic pressure and inhibit The large intestine absorbs water to achieve the effect of treating constipation.

  

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• 2. Insist on exercising: Avoid sedentary, appropriate and active exercise helps bowel movements. Doing daily abdominal contractions and levator ani exercises can improve the function of abdominal muscles and pelvic floor muscles, and also help to improve constipation symptoms

• 3. Cultivate the habit of defecation: The standing up reflex in the morning can promote colon movement and help to produce the urge to defecate. It is recommended that patients with constipation try to defecate every morning or within 2 hours after meals. Develop the habit of regular defecation every day, form a conditioned reflex, and establish a good defecation law. Defecate in time when you have the urge to defecate, so as not to inhibit the urge to defecate and destroy the defecation habit. At the same time, pay attention to avoid the disturbance of defecation habits, insist on defecation carefully, and avoid other tasks such as reading mobile phones and newspapers at the same time.

• 4. Try manual massage: Manual massage can also help increase gastrointestinal motility. Specific method: put one palm on the navel, and the other hand on the back of the hand, and then do a circular massage from the inside to the outside in a clockwise direction, and apply a certain strength, repeated many times, 3 times a day.

• 5. TCM-assisted adjustment: Acupuncture, acupoint application, massage and massage and other TCM external treatment methods can be used to treat Parkinson's disease constipation symptoms, which can avoid the side effects of oral drugs.

• 6. Drug treatment: domestic commonly used drugs include lactulose, polyethylene glycol, senna, Kaisailu, paraffin oil, etc. Polyethylene glycol is a bulk laxative that has a laxative effect by increasing fecal water content and fecal volume and is more effective than lactulose for constipation in patients with Parkinson's disease. Lactulose is safe and well-tolerated for long-term use, and can also be used; Kaisailu helps defecation by softening hard and dry stools and stimulating rectal peristalsis. Others include Cistanche tubulosa extract, which can stimulate the secretion of chloride ions and then lead to the secretion of water and electrolytes. It has good short-term efficacy, high safety and fewer side effects in the treatment of PD constipation. Serotonin agonists such as cisapride, mosapride and tegaserod can improve PD constipation by promoting gastrointestinal motility. They can be selected according to the patient's condition in the early stage of the disease, but their long-term efficacy needs further clinical research. In addition, the researchers found that probiotics significantly improved the symptoms of abdominal pain and bloating in PD patients with constipation.

• 7. Others: Botulinum toxin injection therapy can improve rectal muscle focal dystonia in patients with Parkinson's disease, and it is an effective treatment for Parkinson's disease combined with outlet obstruction constipation. However, since the effects of the toxin subside within 3 months after administration; functional magnetic stimulation of the thoracolumbosacral nerve can improve defecation in patients with Parkinson's disease, but the therapeutic effect is generally maintained for 3 months after the intervention. A large number of medical researches and clinical trials have shown that Cistanche can be very good for the treatment of constipation and Parkinson's disease. Traditional Chinese medicine also believes that Cistanche is a good tonic medicinal material, which can be effectively used for the prevention and treatment of Parkinson's disease and constipation.

  

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