Knowledge

Sirtuins Modulation: A Promising Strategy For HIV-Associated Neurocognitive I...

Abstract: HIV-Associated neurocognitive disorder (HAND) is one of the major concerns since it persists in 40% of this population. Nowadays, HAND neuropathogenesis is considered to be caused by the ...

Gut Microorganisms And Neurological Disease Perspectives Part 3

Another study by Parracho et al. using fluorescent in situ hybridization showed elevated levels of Clostridium hystolyticum in children with ASD compared with healthy children [85]. Clostridium his...

​Cistanche Tubulosa: A Natural Ally in The Prevention Of Alzheimer's Disease

Cistanche tubulosa, widely known for its therapeutic properties, is gaining attention for its potential role in preventing Alzheimer's disease. This article delves into the specific components ...

Single-Cell RNA Sequencing Of Urinary Cells Reveals Distinct Cellular Diversi...

Discussion A limitation of this study is the small number of patients sampled. Sample collections were restricted to new hospital admissions to control for other variables, such as the various medi...

Gut Microorganisms And Neurological Disease Perspectives Part 2

Gut microbiota composition in modulating nervous functions Experiments on germ-free animals have demonstrated that colonization of the gut microbiota is a key requirement for the development of the...

Sleep Disturbances In Chronic Kidney DiseaseⅦ

Sleep disturbances are common in CKD, and their presence has a large impact on morbidity and mortality. Having a low clinical threshold for suspected sleep disturbances in CKD is important to facil...

Sleep Disturbances In Chronic Kidney DiseaseⅥ

Treatment of sleep apnea in patients with CKD In the general population, sleep apnea is treated to improve sleep quality and reduce daily symptoms of fatigue and sleepiness. Treatment options for s...

Sleep Disturbances In Chronic Kidney DiseaseⅤ

Bidirectional relationship between sleep apnea and CKD Extensive evidence supports the concept of a bidirectional relationship between OSA and CKD, as the presence of OSA leads to accelerated decli...

Single-Cell RNA Sequencing Of Urinary Cells Reveals Distinct Cellular Diversi...

Results We performed scRNAseq on urine sediment from eight hospitalized patients with COVID-19 , five with AKI and three without AKI. Four additional urine samples from hospitalized patients withou...

Sleep Disturbances In Chronic Kidney DiseaseⅣ

Prevalence of OSA and CSA in CKD In the general population, the overall prevalence of moderate to severe OSA (AHI>15) is approximately 10%, with some studies reporting prevalences as high as 23%...

Single-Cell RNA Sequencing Of Urinary Cells Reveals Distinct Cellular Diversi...

Abstract Background AKI is a common sequela of infection with SARS-CoV-2 and contributes to the severity and mortality of COVID-19. Here, we tested the hypothesis that kidney alterations induced by...

Sleep Disturbances In Chronic Kidney DiseaseⅢ

Prevalence of RLS in CKD The prevalence of RLS symptoms in the general population is ~5%. RLS symptoms are more common in patients with CKD or renal failure, with widely varying reported prevalence...