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21
Apr, 2023
Immunoglobulin A Mucosal Immunity And Altered Respiratory Epithelium in Cysti...
4. Gaps in Knowledge and Perspectives Studies on patients’ lung tissues show limitations related to the end-stage status of CF patients and the smoking status of controls recruited for tissue sampl...
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21
Apr, 2023
The Role Of PPAR Alpha in The Modulation Of Innate Immunity Part 2
5. PPARα’s Role in the Innate Immunity Effector Processes: ROS/RNS Production An important component of innate immunity in animals is the generation of active forms of oxygen (mainly superoxide) an...
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21
Apr, 2023
Immunoglobulin A Mucosal Immunity And Altered Respiratory Epithelium in Cysti...
Abstract: The respiratory epithelium represents the first chemical, immune, and physical barrier against inhaled noxious materials, particularly pathogens in cystic fibrosis. Local mucus thickening...
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21
Apr, 2023
The Role Of PPAR Alpha in The Modulation Of Innate Immunity Part 1
Abstract: Peroxisome proliferator-activated receptor α is a potent regulator of systemic and cellular metabolism and energy homeostasis, but it also suppresses various inflammatory reactions. In th...
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21
Apr, 2023
Hematopoietic Stem Cell Transplantation For Children With Inborn Errors Of Im...
This is a retrospective analysis of the clinical characteristics of children with inborn errors of immunity who underwent a hematopoietic stem cell transplant (HSCT). Although the mean age at diagn...
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20
Apr, 2023
Modelling The Influence Of Naturally Acquired Immunity From Subclinical Infec...
Incorporation of spatial structure and incidence-dependent human response The non-spatial model was extended to a spatial patch model including the human-mediated movement of dogs and incidence-dep...
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20
Apr, 2023
Modelling The Influence Of Naturally Acquired Immunity From Subclinical Infec...
Abstract Several mathematical models have been developed for canine rabies to explore dynamics and inform control strategies. A common assumption of these models is that naturally acquired immunity...
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20
Apr, 2023
BCG-induced Trained Immunity Enhances Acellular Pertussis Vaccination Respons...
INTRODUCTION Pertussis is a highly transmissible acute respiratory disease caused by the bacterium Bordetella pertussis and has re-emerged as a serious public health issue despite high vaccine cove...
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19
Apr, 2023
Understanding And Exploiting Post-Translational Modifications For Plant Disea...
4. Effectors Disrupt Host PTMs The regulation of PTMs is crucial for plant disease resistance to minimise pathogen establishment. Numerous pathogen effectors target PTM machinery, and some effector...
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19
Apr, 2023
Understanding And Exploiting Post-Translational Modifications For Plant Disea...
Abstract: Plants are constantly threatened by pathogens, so have evolved complex defence signalling networks to overcome pathogen attacks. Post-translational modifications (PTMs) are fundamental to...
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18
Apr, 2023
Nature Of Acquired Immune Responses, Epitope Specificity And Resultant Protec...
Abstract: The primary global response to the SARS-CoV-2 pandemic has been to bring to the clinic as rapidly as possible several vaccines that are predicted to enhance immunity to this viral infecti...
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18
Apr, 2023
Botryllus Schlosseri As A Unique Colonial Chordate Model For The Study And Mo...
Abstract: Understanding the mechanisms that sustain immunological nonreactivity is essential for maintaining tissue in syngeneic and allogeneic settings, such as transplantation and pregnancy toler...