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21
Jul, 2023
Person-Specific Contributions Of Brain Pathologies To Progressive Parkinsonis...
Abstract Background: Mixed-brain pathologies are the most common cause of progressive parkinsonism in older adults. We tested the hypothesis that the impact of individual pathologies associated wit...
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18
May, 2023
Cistanche Deserticola, Take You To Decipher The Silent Killer in Your Father'...
At present, the total number of Parkinson's disease patients in China exceeds 2 million, accounting for about half of the global number of such patients, and there are more males than females. Its ...
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27
Apr, 2023
Role Of TOMM40'523' Polymorphism in Disease Risk And Age At Symptom Onset in ...
Abnormal mitochondrial function is a key process in the pathogenesis of Parkinson’s disease (PD). The central pore-forming protein TOM40 of the mitochondria is encoded by the translocase of the ou...
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26
Apr, 2023
Pathogenic Mechanism Of α-synuclein in A HiPSC Model Of Parkinson's Disease
α-synuclein is an increasingly prominent player in the pathology of a variety of neurodegenerative conditions. Parkinson’s disease (PD) is a neurodegenerative disorder that affects mainly the dopam...
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24
Apr, 2023
An Examination Of Mobile Spinal Cord Stimulators On Treating Parkinson Disease
Abstract In animal models of Parkinson's disease (PD), spinal cord stimulation (SCS) exhibits neuroprotective effects. Recent advancements in SCS technology, most importantly mobile stimulators, al...
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24
Apr, 2023
Group I MGluRs in Therapy And Diagnosis Of Parkinson’s Disease: Focus On MGlu...
Metabotropic glutamate receptors (mGluRs; members of class C G-protein-coupled receptors) have been shown to modulate excitatory neurotransmission, regulate presynaptic extracellular glutamate leve...
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24
Apr, 2023
Group I MGluRs in Therapy And Diagnosis Of Parkinson’s Disease: Focus On MGlu...
Metabotropic glutamate receptors (mGluRs; members of class C G-protein-coupled receptors) have been shown to modulate excitatory neurotransmission, regulate presynaptic extracellular glutamate leve...
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13
Apr, 2023
Piribedil-induced Reversible Pisa Syndrome in A Patient With Lewy Body Dementia
Abstract: Pisa syndrome (PS) has been described for the first time as a side effect of neuroleptic treatment in patients with schizophrenia. After its first description, PS was reported in patients...
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12
Apr, 2023
Biomonitoring Of Mycotoxins in Plasma Of Patients With Alzheimer’s And Parkin...
3. Conclusions We present the results obtained in a first HBM study on the analysis of 19 mycotoxins and metabolites in plasma samples from healthy and patient (AD and PD) volunteers in La Rioja (S...
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12
Apr, 2023
Biomonitoring Of Mycotoxins in Plasma Of Patients With Alzheimer’s And Parkin...
2. Results and Discussion 2.1. LC-MS/MS Analysis Due to their different physicochemical characteristics, mycotoxins were divided for chromatographic separation into two groups (see material and met...
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12
Apr, 2023
Biomonitoring Of Mycotoxins in Plasma Of Patients With Alzheimer’s And Parkin...
Abstract: Exposure to environmental contaminants might play an important role in neurodegenerative disease pathogenesis, such as Parkinson´s disease (PD) and Alzheimer´s disease (AD). For the first...
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30
Mar, 2023
Advances in Parkinson’s Disease Drugs
Parkinson’s disease (PD) is the second most common neurodegenerative age-related disorder worldwide after Alzheimer’s disease [1–3], in which environmental and genetic factors play a pivotal role. ...