4 Types Of People Who Are Prone To Parkinson's Disease, And 4 Major Symptoms Of Parkinson's, You Must Understand
Apr 08, 2022
Parkinson's disease is a very common degenerative disease of the elderly nervous system, which often manifests as involuntary tremors at rest, muscle stiffness in limbs, slow movement, and postural balance disorders. To put it simply, it is because the brain and nerves are aging, but everyone will grow old, and not everyone will get this disease.
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Who is at risk for Parkinson's disease?
1. The elderly.
Parkinson's disease mostly occurs in people over 60 years old. Although it is medically known to be caused by a decrease in the level of dopamine in the nigrostriatal of the brain, the cause of nerve cell decline is not very clear.
2. Genetics.
According to medical evidence, Parkinson's disease has certain heredity, but heredity does not mean that the disease will definitely occur, but the existence of genetic factors will make Parkinson's disease more likely than normal people.
3. Traumatic brain injury.
When the brain is impacted by an external force, it will cause damage to the nerve cells in the brain. Epilepsy and Parkinson's disease are all related to traumatic brain injury.
4. Long-term exposure to toxic chemicals.
Such as pesticides, manganese, mercury, lead, etc. will affect brain-induced Parkinson's. Usually, if there is exposure to pesticides, toxic chemicals, or some heavy metals, may cause chronic poisoning and eventually lead to the occurrence of Parkinson's disease.
Medicine believes that the early symptoms of decreased sense of smell, emotional instability, anxiety, trembling of writing, smaller and smaller writing, and frequent dancing and kicking may indicate whether Parkinson's disease is present.
4 symptoms of Parkinson's disease
Trembling. The trembling of the hands at rest is the earliest symptom of Parkinson's disease. The patient's tremor first occurred in the hand, and one side of the hand was often found to be involuntarily moving like "rubbing balls". As long as it is controlled deliberately, it may disappear. Because of this, many people will ignore the occurrence of the disease at first. , I thought I was shaking because I was tired. When the patient is nervous, the tremor will also be more obvious, and in severe cases, there will be tremors of the head, lips, tongue, etc. According to medical statistics, patients experience tremors 4 to 6 times per second.
Rigid muscles. In the early stage, muscles are tight and joints are stiff from one side, so a big feature of Parkinson's disease is the "mask face". Slow stiffness spreads throughout the body causing slow, difficult movements such as bending forward, walking, necking, and turning around.
Move slowly. Due to the increased muscle tension, the patient becomes slow to get up, turn over, and walk, and even the fine movements of the hand cannot be completed, such as buttoning buttons and tying shoelaces.
Balance disorder. The body is unable to maintain balance, and the center of gravity is unstable when walking. The symptoms of Parkinson’s are not just that. These four symptoms are only the primary and main symptoms of movement disorders. Many Parkinson’s patients also experience dementia, hallucinations, delusions, aggression, insomnia, depression, and Changes in other mental disorders such as anxiety.
In the past, the treatment of Parkinson's disease was mainly based on drug treatment to control symptoms, but because Parkinson's disease will become more and more serious with age, the drug itself has a certain tolerance, and long-term medication will also lead to the need for The amount of medicine is increasing, and surgery is only selected when the medicine cannot be controlled or there are serious side effects. However, a recent Parkinson's surgery has also attracted the attention of the majority of patients. By using a pacemaker to control the symptoms of Parkinson's disease, the cure rate for Parkinson's disease has reached 97%, which is undoubtedly a cure for Parkinson's disease. A big breakthrough.
Rehabilitation training for Parkinson's disease
1. Facial recovery exercise. The stiffness of the facial muscles in Parkinson's disease leads to a "mask face" with a rigid facial expression. The stiffness of the facial muscles can be relieved by repeated daily exercises such as frowning, opening the eyes hard, bulging the cheeks, and whistling.
2, head and neck exercises. You can lower your head back and forth, look up, turn left and right, swing left and right, etc. to relieve neck stiffness.
3. Hand exercise. Because the stiffness of the muscles leads to severe flexion of the finger joints, excessive flexion of the fingers can be relieved by repeated use of hand movements. Such as writing, grasping training, knitting, etc.
4. Walk. In order to restore the balance of the body posture, you can practice standing on one foot or walking with a raised foot.
For Parkinson's patients, any exercise should be started early, before severe limitation of joint motion or severe muscle atrophy occurs. The symptoms of Parkinson's disease can be alleviated by early exercise and prompt stimulation of brain and muscle recovery.
Acteoside(Verbascoside) in Cistanche can significantly improve the behavioral performance of patients with Parkinson's disease, increase the content of dopamine transmitters and the number of dopaminergic neurons, and the level of a-synuclein protein in the substantia nigra striatum. Acteoside can induce SH in rotenone -SY5Y cell injury has a neuroprotective effect, and its mechanism of action is related to reducing the degradation of Parkinson’s disease-related proteins and inhibiting the formation of α-synuclein dimers; verbascoside(acteoside) can reduce the SH-SY5Y injury induced by the neurotoxin MPP+ The level of reactive oxygen species, increase the expression level of Bcl-2, and reduce the activity of caspase-3 indicate that the compound can effectively inhibit the apoptosis of SH-SY5Y cells. The mechanism of action is to reduce the level of intracellular reactive oxygen species and inhibit caspase-3. Activity is related to maintaining the high-energy state of mitochondrial membrane potential; verbascoside can also have obvious cytoprotective effects on brain cell apoptosis in patients with Parkinson's disease, and can effectively resist Parkinson's disease.
