A Comprehensive Inventory Of Drugs And Measures For Lowering Urinary Protein

The kidneys are the "filters" of the human body. After the glomerular filtration membrane is damaged, protein in the blood leaks into the urine, which is proteinuria. Diseases prone to proteinuria include diabetic nephropathy, glomerulonephritis, lupus nephritis, etc.

Click to Cistanche for kidney disease

Proteinuria is the result of kidney damage, but the high urinary protein will in turn damage the kidneys, so urinary protein must be actively controlled.

Today, we will summarize several guidelines and take stock of the drugs and measures that can reduce urinary protein.

Urinary protein-lowering drugs that can be used in most kidney diseases can be said to be the basic drugs for kidney diseases, including sartan antihypertensive drugs, protein-type antihypertensive drugs, and gliflozin-type antihyperglycemic drugs.

1. Sartans or Primlins: Sartans include valsartan, irbesartan, telmisartan, candesartan, measartan, etc. Primlinds include benazepril and fosinopril. Lee, ramipril, etc. In addition to lowering blood pressure, these two types of drugs can also lower urinary protein. Kidney patients should use them even if their blood pressure is not high but they have urinary protein. However, these two types of drugs cannot be used together.

2. Digliflozin: including dapagliflozin, empagliflozin, canagliflozin, etc. In addition to lowering blood sugar, these drugs also lower urinary protein. They are needed for diabetic nephropathy and nephropathy without diabetes, such as glomerulonephritis. Use it too.

Drugs used to reduce urinary protein in diabetic nephropathy include fenceline and semaglutide

1. Fenelidone: This is a third-generation aldosterone receptor antagonist. It is currently used for the treatment of diabetes-related nephropathy. Studies have found that it is also very effective in non-diabetic nephropathy. It is expected that it may be approved for non-diabetic nephropathy next year. Such as the treatment of glomerulonephritis.

2. Semaglutide: can reduce urinary protein in diabetic nephropathy.

Drugs used to reduce urinary protein in autoimmune-related kidney diseases such as glomerulonephritis, lupus nephritis, purpura nephritis, etc. include hormones and immunosuppressants.

1. Hormones: It is recommended to use medium-effective hormones such as methylprednisolone, prednisone, triamcinolone, etc. For IgA nephropathy, the newly launched budesonide enteric-coated capsules can also be used.

2. Immunosuppressants: cyclophosphamide, cyclosporine, tacrolimus, mycophenolate mofetil, etc.

Among the above-mentioned drugs, sartans, pruriflozin, gliflozin, and fenelinone, in addition to lowering urinary protein, can also delay kidney damage, which is commonly said to protect the kidneys, so it is recommended to take them for a long time.

Moderate protein diet

A large amount of proteinuria will lead to hypoalbuminemia. Some people will naturally think of eating more protein to supplement the protein. This is a misunderstanding. If you don't "block the leakage of the kidneys" and just supplement protein blindly, the more you eat, the more leakage will occur, which will aggravate kidney damage, so protein intake must be controlled.

How Does Cistanche Treat Kidney Disease?

Cistanche is a traditional Chinese herbal medicine used for centuries to treat various health conditions, including kidney disease. It is derived from the dried stems of Cistanche deserticola, a plant native to the deserts of China and Mongolia. The main active components of cistanche are phenylethanoid glycosides, echinacoside, and acteoside, which have been found to have beneficial effects on kidney health.

Kidney disease, also known as renal disease, refers to a condition in which the kidneys are not functioning properly. This can result in a buildup of waste products and toxins in the body, leading to various symptoms and complications. Cistanche may help treat kidney disease ase through several mechanisms.

Firstly, cistanche has been found to have diuretic properties, meaning it can increase urine production and help eliminate waste products from the body. This can help relieve the burden on the kidneys and prevent the buildup of toxins. By promoting diuresis, cistanche may also help Reduce high blood pressure, a common complication of kidney disease.

Moreover, cistanche has been shown to have antioxidant effects. Oxidative stress, caused by an imbalance between the production of free radicals and the body's antioxidant defenses, plays a key role in the progression of kidney disease. ies help neutralize free radicals and reduce Oxidative stress, thereby protecting the kidneys from damage. The phenylethanoid glycosides found in cistanche have been particularly effective in scavenging free radicals and inhibiting lipid peroxidation.

Additionally, cistanche has been found to have anti-inflammatory effects. Inflammation is another key factor in the development and progression of kidney disease. Cistanche's anti-inflammatory properties help reduce the production of pro-inflammatory cytokines and inhibit the activation of inflammation mandatory pathways, thus alleviating inflammation in the kidneys.

Furthermore, cistanche has been shown to have immunomodulatory effects. In kidney disease, the immune system can be dysregulated, leading to excessive inflammation and tissue damage. Cistanche helps regulate the immune response by modulating the production and activity of immune cells, such as T cells and macrophages. This immune regulation helps reduce inflammation and prevent further damage to the kidneys.

Moreover, cistanche has been found to improve renal function by promoting the regeneration of renal tubes with cells. Renal tubular epithelial cells play a crucial role in the filtration and reabsorption of waste products and electrolytes. In kidney disease, these cells can be damaged, leading to damaged renal function. Cistanche's ability to promote the regeneration of these cells helps restore proper renal function and improve overall kidney health.

In addition to these direct effects on the kidneys, cistanche has been found to have beneficial effects on other organs and systems in the body. This holistic approach to health is critical in kidney disease, as the condition often affects multiple organs and systems. che has been shown to have protective effects on the liver, heart, and blood vessels, which are commonly affected by kidney disease. By promoting the health of these organs, cistanche helps improve overall kidney function and prevent further complications.

In conclusion, cistanche is a traditional Chinese herbal medicine used for centuries to treat kidney disease. Its active components have diuretic, antioxidant, anti-inflammatory, immunomodulatory, and regenerative effects, which help improve renal function and protect the kidneys from further damage. , cistanche has beneficial effects on other organs and systems, making it a holistic approach to treating kidney disease.