Parkinson's Patients Should Not Take Drugs Indiscriminately, Otherwise It May Aggravate The Condition!

Drug therapy As a routine treatment for Parkinson's disease, daily medication for Parkinson's disease patients is extremely important, but for Parkinson's disease patients, the use of some drugs may aggravate the symptoms of Parkinson's disease. For ordinary people, the use of these drugs may cause symptoms of Parkinson's. Do these drugs have the following categories?

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       1. Antipsychotics: Common drugs include: Delixin, Aripiprazole, Perphenazine, Fluphenazine, Haloperidol, Olanzapine, Risperidone, Fluoxetine, Tiapride, Sulbil, et al.

       2. Digestive system drugs: Common drugs include: metoclopramide (metoclopramide), cisapride, mosapride, famotidine, etc.

       3. Antihypertensive drugs: reserpine, Beijing Antihypertensive No. 0 (containing reserpine), etc.

       4. Calcium channel blockers: Flunarizine (Sibilin), Cinnarizine, etc.

       5, antiarrhythmic drugs: amiodarone.

       6. Anti-allergic drugs: promethazine (Phenergan), loratadine.

The above is just a list of some common drugs that may cause Parkinson's syndrome, but you don't need to be too nervous. Although the above drugs may cause Parkinson's syndrome, they are not 100% caused, as long as the short-term appropriate amount is under the guidance of a doctor. Medication is relatively safe.

Even if the symptoms of Parkinson's have already appeared due to taking a certain drug, as long as it is detected and treated in time, 90% of the patients will gradually relieve their Parkinson's symptoms to disappear after the drug is stopped, and only 10% of the patients are stopped. Parkinson's symptoms persisted and even worsened after the drug.

In a word, it is necessary to fully understand and pay attention to drug-induced Parkinson's syndrome, so as to achieve early detection, early diagnosis, and early treatment. In addition, the above drugs may aggravate the symptoms of primary Parkinson's disease, so Parkinson's patients should be cautious when taking drugs to prevent drug-induced symptoms from worsening.

What are the symptoms of Parkinson's disease?

      1. Tremors are more common in the head and limbs, the most obvious in the hands, and the fingers show a thick resting tremor (a typical manifestation is a "rubbing nine-like" tremor between the thumb and the flexed index finger. With the development of the disease, tremor gradually spreads to the entire limb, even the trunk, and extends from one upper limb to the ipsilateral lower limb and the opposite upper and lower limbs. The lower jaw, lips, tongue, and head are generally affected finally.

      2. Muscle stiffness increases the tension of extensors and flexors, and there is a sense of gear-like or lead-like resistance during passive movement, which is called gear-like ankylosis or lead-like ankylosis, respectively.

      3. Movement disorders are related to muscle stiffness, such as dysphonia caused by the stiffness of the articulatory muscle, and difficulty in daily life due to the stiffness of the finger muscles (such as difficulty in daily life, washing, eating, etc.).

      Fourth, other irritable, occasionally impulsive behavior; sweating, saliva, sebaceous gland fluid secretion increased; cerebrospinal fluid, urine dopamine, and its metabolites decreased.

      5. Posture and gait The face is rigid and looks like a mask; the head is tilted forward, the trunk is bent forward, the elbow and knee joints are slightly flexed; the walking distance is small, the first step is slow, and the faster and faster, the gait is panic. , the two upper limbs do not swing back and forth.

It can be seen from this that Parkinson's disease will seriously affect the life of patients, so I hope that after understanding the symptoms of Parkinson's disease after aggravation, we can understand the problems that Parkinson's disease will bring to our lives, and we can also early disease control.

For the treatment of Parkinson's disease, drugs are always irreplaceable. Many Parkinson's patients even need to take drugs for a long time. A reasonable and correct way plays a pivotal role in Parkinson's patients. TCM physician Wang Shilong concluded through his 20-year clinical experience in treating patients with Parkinson's disease: "Wulong Tremor Decoction" has a very good inhibitory effect on the treatment of Parkinson's patients, and in the process of taking drug treatment, it can It is very good to avoid the side effects caused by western medicine! The effect of long-term use of the drug is reduced, and the effect of the drug is more stable.

Acteoside in Cistanche can significantly improve the behavioral performance of patients with Parkinson's disease, increase the content of dopamine transmitters and the number of dopaminergic neurons, and the level of a-synuclein protein in the substantia nigra striatum. Verbascum glycosides can induce SH in rotenone -SY5Y cell injury has a neuroprotective effect, and its mechanism of action is related to reducing the degradation of Parkinson’s disease-related proteins and inhibiting the formation of α-synuclein dimers; verbascoside can reduce the SH-SY5Y injury induced by the neurotoxin MPP+ The level of reactive oxygen species, increase the expression level of Bcl-2, and reduce the activity of caspase-3 indicate that the compound can effectively inhibit the apoptosis of SH-SY5Y cells. The mechanism of action is to reduce the level of intracellular reactive oxygen species and inhibit caspase-3. Activity is related to maintaining the high-energy state of mitochondrial membrane potential; verbascoside can also have obvious cytoprotective effects on brain cell apoptosis in patients with Parkinson's disease, and can effectively resist Parkinson's disease.

For more information:ali.ma@wecistanche.com