Women Are More Prone To Senile Dementia! What Are The Gender Differences in Brain Function?

Among the 5 million Alzheimer's disease patients in the United States, women make up two-thirds. Why does the incidence rate of Alzheimer's disease show such a significant gender difference? Some people say that this is because women have a longer lifespan. However, some scientists believe there are other explanations. Not only Alzheimer's disease but also many neurodegenerative diseases have gender differences in risk and treatment effectiveness. However, even with the most advanced technology today, neuroscientists find it difficult to completely distinguish gender differences in brain function.

Effects of Cistanche-Anti Alzheimer's disease

1. Lifetime difference

Researchers from the Mayo Clinic tested the levels of amyloid protein in the brains of 1246 cognitively healthy volunteers aged 30 to 95. When researchers compared the hippocampus of males and females, the experimental results were not optimistic for males - for participants over 40 years old, males had smaller hippocampus and poorer memory than females. However, there is no significant difference in amyloid protein levels between male and female brains in any age group. Given that women do not exhibit a higher biochemical risk of developing Alzheimer's disease, researchers believe that differences in incidence may stem from longer lifespans in women.

Benefits of cistanche tubulosa-Anti Alzheimer's disease

2. Differences in gene expression levels

However, scientists hope to find other explanations beyond lifespan. Researchers from the University of Kansas tested the expression levels of 182 genes involved in energy supply - these genes regulate glucose and amyloid metabolism in the aging brain. In the development of Alzheimer's disease, there are often symptoms of reduced energy supply and accumulation of amyloid protein. Their research found that as age increases, these changes in the brain of female mice are particularly significant and appear much earlier than those in males.

One hypothesis is that overall changes in the female brain may reduce energy utilization in neurons and slow down the clearance process of amyloid. Among the genes analyzed by the researchers, 44.2% of gene expression levels have undergone significant changes in the early stages of female life -6-9 months. These changes increase the risk of Alzheimer's disease in female brains. However, whether these observations in mice can be extrapolated to humans remains to be studied.

3. Differences in protein activity

In Parkinson's disease, the degeneration or death of dopamine neurons results in a decrease in dopamine levels, leading to motor dysfunction. In addition, dopamine transporter protein (DAT) levels are reduced in Parkinson's patients. Researchers from the University of Turku in Finland examined the activity of DAT in both normal and Parkinson's diseased men and women and found that in the caudate nucleus, women have higher DAT activity than men, which is a key link in the dopamine network in the brain. This effect may protect women from Parkinson's disease. This study may partially explain why the risk of Parkinson's disease in men is almost twice that of women.

Cistanche deserticola efficacy-Anti Alzheimer's disease

4. tube flower Cistanche helps you stay away from dementia

Research has shown that the various chemical components contained in Cistanche deserticola, such as phenylethanol glycosides, lignans and their glycosides, polysaccharides, etc., have potential pharmacological effects. Phenylethanol glycosides are the main active ingredients in Cistanche deserticola, which have various functions such as anti-adverse stimuli, enhancing learning and memory, antioxidation, and assisting yang. These components may have a positive effect on the prevention and treatment of senile dementia.

In the prevention of senile dementia, Cistanche deserticola extract can display nerve growth factor-like activity and strong neuroprotective effects by promoting axonal growth. In addition, polysaccharides from Cistanche deserticola can increase the activity of superoxide dismutase (SOD) in serum and lungs, reduce the concentration of nitric oxide (NO), inhibit apoptosis of lung tissue cells, and have an improving or delaying effect on the degenerative changes of lung tissue cells in aging mice.

cistanche-prevent Alzheimer's disease 

Click here to view  Cistanche Improving Memory and Prevent Alzheimer's Disease products

【Ask for more】 Email:cindy.xue@wecistanche.com /  Whats App:  0086 18599088692 /  Wechat:  18599088692

In the treatment of senile dementia, total glycosides of Cistanche deserticola have antioxidant activity, which can increase the activity of superoxide dismutase (SOD) in brain tissue, reduce the content of malondialdehyde (MDA), and protect brain tissue from oxidative stress damage. In addition, total glycosides of Cistanche deserticola can improve the spatial learning and memory ability of vascular dementia model rats, as well as the memory impairment induced by D-galactose and aluminum in mice.

Clinical studies have shown that the treatment of Cistanche deserticola total glycoside capsules can delay cognitive decline, and hippocampal volume atrophy, and reduce the levels of total tau protein and inflammatory factors in the cerebrospinal fluid of patients with moderate Alzheimer's disease. This indicates that Cistanche deserticola has potential application value in the treatment of elderly dementia.

However, the low bioavailability of active ingredients in Cistanche deserticola, such as Acteoside and Echinacoside, limits its clinical efficacy. To improve the bioavailability of Cistanche deserticola, traditional Chinese medicine preparations can be improved by using methods such as liposomes, nanoparticles, phospholipid complexes, etc.

cistanche-prevent Alzheimer's disease 

In summary, Cistanche deserticola, as a traditional Chinese medicinal herb, has shown certain potential in the prevention and treatment of senile dementia.

The method of eating is simple and easy to adhere to. Steamed rice, boiled Congee and stewed soup are cut into two pieces and thrown in.

Many of the health and wellness habits we have been advocating for are ultimately abandoned due to being too troublesome and conflicting with our daily habits.

However, using Cistanche tubulosa to prevent dementia, reduce blood pressure, and calm the nerves can be as long as you cook at home, because this health-preserving method does not need to change our life rules, and it can be eaten by frying, cooking Congee, and cooking broth.