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24
May, 2023
TUNING THE TUMOR MICROENVIRONMENT BY REPROGRAMMING TREM1+ MYELOID CELLS TO UN...
Background The tumor microenvironment (TME) often contains high levels of suppressive myeloid cells that contribute to innate checkpoint inhibitor (CPI) resistance. Pionyr ’s Myeloid Tuning approac...
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23
May, 2023
Aptamer-Based Strategies To Boost Immunotherapy in TNBC Part 2
In addition, aptamers tolerate several chemical modifications that improve targeting efficacy, pharmacokinetic profile, and stability in biological environments, which are required for their in viv...
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23
May, 2023
Aptamer-Based Strategies To Boost Immunotherapy in TNBC Part 1
Simple Summary: Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype with poor outcomes and limited therapeutic options. It is characterized by a more pronounced immunogenici...
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23
May, 2023
Impacts Of Vitamin C And D Supplement On COVID-19 Treatment: Possible Patho-m...
Abstract Background A balanced diet and nutrition greatly influence our immune system’s ability and regulate the risk and severity of infections. This review presented the possible pathomechanisms ...
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23
May, 2023
Clinical Characteristics Of Mpox Infection in Individuals Who Received A Firs...
ABSTRACT Introduction A key part of the response to the pox (monkeypox) epidemic has been the vaccination campaign targeted at gay, bisexual, and other men who have sex with men (GBM), including pe...
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19
May, 2023
Emerging Roles Of Motile Epidermal Chloroplasts in Plant Immunity
Abstract: The plant epidermis contains atypical small chloroplasts. However, the physiological role of this organelle is unclear compared to that of large mesophyll chloroplasts, the well-known fun...
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19
May, 2023
Three Harm‑Based Arguments For A Moral Obligation To Vaccinate Part 2
The Obligation Below the Threshold The argument that obligations to vaccinate are strongest around the herd immunity threshold leaves us with a counterintuitive implication. If there are a signific...
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19
May, 2023
Three Harm‑Based Arguments For A Moral Obligation To Vaccinate Part 1
Abstract A particularly strong reason to vaccinate against transmittable diseases, based on considerations of harm, is to contribute to the realization of population-level herd immunity. We argue, ...
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19
May, 2023
Research Progress Of ATGs Involved in Plant Immunity And NPR1 Metabolism
Abstract: Autophagy is an essential pathway of degrading excess and abnormal proteins and organelles through their engulfment into autophagosomes that subsequently fuse with the vacuole. Autophagy-...
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17
May, 2023
CaWRKY30 Positively Regulates Pepper Immunity By Targeting CaWRKY40 Against R...
2.5. CaWRKY30 Transient Over-Expression Stimulated HR-Like Cell Death, Production of H2O2, and Transcriptional Upregulation of Immunity-Related Marker Genes The VIGS experiments indicated that CaWR...
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17
May, 2023
CaWRKY30 Positively Regulates Pepper Immunity By Targeting CaWRKY40 Against R...
Abstract: The WRKY transcription factors (TFs) network is composed of the WRKY TFs’ subset, which performs a critical role in the immunity regulation of plants. However, the functions of WRKY TFs’ ...
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17
May, 2023
Immunity After COVID-19 Vaccinations in Immunocompromised Patients With Psori...
Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevie...