Cytopharmacological Mechanism Of Antioxidant Activity Of Cistanche Deserticola
Jul 23, 2024
People use oxygen for respiration and metabolism, but when the body is using oxygen for certain metabolic reactions, it inevitably produces some unstable substances. These unstable substances are all "transformations" of oxygen, and their personalities are very lively. They do not like to stay in place and even like to attack others. Due to their personality of not liking to be restrained, they are called free radicals. The unrestrained nature of free radicals is certainly a headache, but sometimes the human body needs to use the activity of free radicals to eliminate certain invading microorganisms or abnormal cells. Therefore, lively free radicals also have their lovely side. When the concentration of free radicals in the human body is not very high, the body has a sophisticated system to eliminate these free radicals, which is called the antioxidant system. Unfortunately, the living space and form can cause a significant increase in the concentration of free radicals in the body, such as smoking, air pollution, water pollution, radiation, pesticides, high life stress, excessive exercise, etc. These situations that can increase the concentration of free radicals are called oxidative stress. The higher the oxidative pressure, the higher the concentration of free radicals in the body, and at this time, the antioxidant system in the body will face a crisis of insufficient use.
Desert living cistanche-Antioxidant
Having antioxidant activity refers to any oxidation reaction that can effectively inhibit free radicals at low concentrations. Its mechanism of action can be direct action on free radicals or indirect consumption of substances that are prone to generating free radicals, preventing further reactions from occurring. More and more research shows that antioxidant is an important step in preventing aging, as free radicals or oxidants can break down cells and tissues, affect metabolic function, and cause various health problems. If excessive oxidative free radicals can be eliminated, many diseases caused by free radicals and aging can be prevented. For example, common cancers, arteriosclerosis, diabetes, cataracts, cardiovascular diseases, senile dementia, arthritis, etc. are all considered to be related to free radicals. Therefore, an increasing number of antioxidant and anti-aging health products are highly favored, and Cistanche deserticola is also highly regarded for its antioxidant properties.
Desert living cistanche-Antioxidant
Research by Li Linlin et al. has shown that the total glycosides of Cistanche deserticola can enhance the activity of selenium glutathione peroxidase and SOD (superoxide dismutase) in the brain, serum, and liver of aging organisms, reduce the content of lipid peroxides and lipofuscin in the cardiovascular system, exert antioxidant effects on body tissues, and protect against acute cerebral hypoxia and myocardial damage. The phenylethanoid glycosides in Cistanche deserticola exhibit strong antioxidant activity due to their ability to scavenge DPPH (1,1-diphenyl-2-trinitrophenylhydrazine) free radicals. Ergosterol glycoside inhibits liver failure induced by D-gal (D-galactosamine) and LPS (lipopolysaccharides) by clearing reactive oxygen species in the body. Xinjiang Cistanche glycoside B also has similar effects, which can protect against DNA damage caused by peroxidation by reducing the accumulation of intracellular reactive oxygen species induced by MPP+. Phenylethanol total glycosides contain multiple phenolic hydroxyl groups in their molecules, which can bind to free radicals in the body, thereby avoiding the accumulation of free radicals in the body and protecting the body from oxidative damage. They are the main effective ingredients for anti-aging and antioxidant effects. Research has shown that Cistanche deserticola can delay the aging of animal skin by increasing the content of hydroxyproline, collagen fibers, and skin elasticity.
Benefits of cistanche tubulosa-inhibit tyrosinase expression
In addition, Cistanche deserticola also has whitening effects.
In the field of beauty, the whitening effect of Cistanche deserticola is gradually receiving attention. Its main active ingredient is phenylethanol glycoside compounds, which have significant whitening effects. Phenylethanolamine can inhibit the activity of tyrosinase, which is a key enzyme in melanin production, thereby reducing melanin production and achieving the goal of whitening the skin.
The anti-aging effect of Cistanche deserticola
In addition to whitening, Cistanche deserticola also has anti-aging effects. Research has found that Cistanche deserticola extract can eliminate free radicals and has antioxidant capacity. At the same time, it reduces the expression levels of collagenase and elastase mRNA, inhibits the activity of these enzymes, and helps to delay skin aging.
Benefits of cistanche tubulosa-inhibit tyrosinase expression
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The application of Cistanche deserticola in cosmetics
The development and application of Cistanche deserticola in the cosmetics field has gradually begun. It has good effects in whitening, anti-aging, sun protection, anti-inflammatory, moisturizing, and antibacterial aspects. The phenylethanolamine glycosides in Cistanche deserticola not only absorb ultraviolet rays, but also have antioxidant, DNA damage repair, and reduced cell apoptosis effects, which have good application value in sunscreen cosmetics.
The moisturizing effect of Cistanche deserticola
Moisturizing is a fundamental requirement of skincare, and Cistanche deserticola extract has excellent water-holding capacity. Research has shown that Cistanche deserticola extract can increase the moisture content of the stratum corneum, reduce water loss, and maintain the normal function of the skin barrier.
The antibacterial effect of Cistanche deserticola
Cistanche deserticola also has good antibacterial effects, which are crucial for preventing microbial growth and reproduction in cosmetics. Cistanche deserticola polysaccharides have inhibitory effects on the growth of various bacteria and fungi and can be used as natural preservatives.
Safety and quality identification of Cistanche deserticola
Although Cistanche deserticola has various beauty and beauty benefits, its main active ingredients are greatly influenced by factors such as species and place of origin. Therefore, when using Cistanche deserticola in cosmetics, attention should be paid to its quality identification and quality standards.
Benefits of cistanche tubulosa-inhibit tyrosinase expression
epilogue
Cistanche deserticola, a precious traditional Chinese medicine for prolonging life and beauty, has been scientifically proven to have effects in whitening, anti-aging, sun protection, moisturizing, and antibacterial properties. With further research on the active ingredients of Cistanche deserticola, its application prospects in cosmetics will be even broader.
With the improvement of people's health awareness, the antioxidant effect of Cistanche deserticola has gradually penetrated people's hearts, greatly promoting the research and development of clinical drugs, health products, and cosmetics of Cistanche deserticola, and also increasing its market share in the field of traditional Chinese medicine health products and traditional Chinese medicine.
