Taking You Deeper Into Cistanche Deserticola - Total Glycosides Of Cistanche Deserticola
Aug 08, 2023
If you have paid attention to me, I believe you are not unfamiliar with Cistanche deserticola. You know that Cistanche deserticola has rich nutrients and can nourish our bodies in many ways, but do you know why it has these effects? Who is exerting these effects again - this issue takes you into the total glycosides of Cistanche deserticola, let's take a look together!

Phenylethanol glycoside is the main active component of Cistanche tubulosa
What are the total glycosides of Cistanche deserticola?
What is the composition of total glycosides in Cistanche deserticola?
What are the effects of total glycosides from Cistanche deserticola?
What are the total glycosides of Cistanche deserticola?
The total glycosides of Cistanche deserticola are similar to ginsenosides and belong to the triterpenoid saponin class compounds. Both are extracted from traditional Chinese medicine, and there are some similarities and differences between the two. Please refer to the following.

Main Chemical Constituents of Cistanche herb
Q1 similarity?
1. Both contain similar saponin components, such as Rb1, Rg1, etc.
2. Both can enhance the body's anti-fatigue ability.
3. Both can regulate the body's endocrine system and enhance immune function.
4. Both have certain antioxidant effects.
5. In traditional Chinese medicine, it belongs to the category of tonics and can be used to nourish the body.
Q2 difference?
1. Different sources: ginsenosides come from ginseng, while total glycosides from cistanche come from cistanche.
In terms of drug efficacy, overall, ginsenosides are slightly stronger than the total glycosides of Cistanche deserticola.
The above figure shows triterpenoid saponin compounds
What is the composition of total glycosides in Cistanche deserticola?
The main components of total glycosides in Cistanche deserticola include R0, Rb1, Rb2, Rc, Rd, Re, Rg1, and other components. But there are significant differences in proportion:
Specific component content
1. Cistanche saponin Rb1: The quantity is the most abundant, accounting for about 20% of the total glycosides in Cistanche deserticola.
2. The content of saponin Rc in Cistanche deserticola takes second place, accounting for approximately 10-15%.
3. Cistanche saponin Rb2: accounts for approximately 8-10%.
4. Cistanche saponin Rg1 and Cistanche saponin Re account for approximately 6-8%.
5. Cistanche saponin R0: accounts for about 5%.
6. Cistanche Saponin Rd: accounts for approximately 2-4%.
Among the above components, Rb1, Rc, and Rb2 are the main components of total glycosides in Cistanche deserticola. Among them, Rb1 and Rg1 have the strongest pharmacological effects.
Note: The composition ratio of total glycosides may vary slightly depending on the variety, origin, and processing method of Cistanche deserticola.
Having said so much earlier, I believe everyone is most concerned about this last point. Without further ado, let's get to the point.
What role do the total glycosides of cistanche tubulosa play?
In the beginning, when comparing with total saponins of ginseng, we mentioned that total saponins of Cistanche deserticola can enhance the body's anti-fatigue ability, regulate the body's endocrine system, enhance immune function, and have certain antioxidant effects. In addition to these, it also has functions such as lowering blood sugar, lowering blood lipids, and protecting the liver. Below, we will provide a detailed introduction.
1. Enhance the body's anti-fatigue ability

Desert living cistanche herb-anti-fatigue
1) The total glycosides of cistanche herb can promote glycogen synthesis, increase liver glycogen storage, provide more lasting energy for the body, and delay the generation of fatigue.
2) The total glycosides of cistanche herb can promote the secretion of hormones such as androstenedione and testosterone in the corpus luteum, which can enhance physical strength and resist fatigue.
2. Enhance immune function

cistanche benefits for men-strengthen immune system
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1) Regulating the proportion of immune cells in the body: Total glycosides of Cistanche deserticola can promote the generation of immune cells such as T lymphocytes and natural killer cells, increase the total number of immune cells, and enhance immune monitoring ability.
2) Increase splenic lymphocytes: Total glycosides of Cistanche deserticola can promote an increase in the number of splenic lymphocytes and enhance the body's immune response to antigens.
3) Stimulating the secretion of immune factors: Total glycosides of Cistanche deserticola can promote the production and release of immune factors such as interferon, complement, and lysozyme, thereby improving the level of immune response.
3. Antioxidant effect

Effects Of cistanche tubulosa—Antioxidant
1) Activating the antioxidant enzyme system: Cistanche glycosides can enhance the activity of antioxidant enzymes such as superoxide dismutase and glutathione peroxidase, enhancing the body's antioxidant enzyme system.
2) Chelated transition metal ions: The total glycosides of Cistanche deserticola contain o-diphenol groups, which can form stable chelates with transition metal ions and reduce the production of oxygen free radicals.
4. Reduce blood sugar
1) Increase insulin sensitivity: Total glycosides of Cistanche deserticola can increase the number and affinity of insulin receptors, enhance tissue sensitivity to insulin, enhance the effect of insulin, and thus lower blood sugar.
2) Inhibiting liver glycogen decomposition and glycogenesis can inhibit the activity of liver glycogen phosphorylase and reduce glycogen decomposition; It can also inhibit the key rate-limiting enzyme glutamine-6-phosphatase, inhibit liver glycogenesis, and lower blood sugar.
3) Increase glucose uptake and utilization: Total glycosides of cistanche plant can increase the uptake and utilization of glucose by muscle and adipose tissue, and lower blood sugar levels
5. Lipid-lowering
1) Inhibition of fat synthase: Total glycosides of cistanche plant can inhibit the activity of key enzymes in fat synthesis, such as acetyl CoA carboxylase, and reduce fat synthesis.
2) Increase fat breakdown and utilization: Total glycosides of cistanche planta can promote fat breakdown and utilization in adipose tissue β Oxidation increases the utilization and consumption of fat.
6. Protecting the liver and protecting the liver

cistanche benefits for men-Maintaining the liver
1) Antioxidant, reducing liver oxidative damage. Cistanche deserticola total glycosides have antioxidant components that can eliminate excess oxygen free radicals in the body, reduce damage to the liver, and play a protective role in the liver.
2) Inhibiting replication of hepatitis virus Total glycosides of Cistanche deserticola has a certain inhibitory effect on some hepatitis viruses, such as hepatitis B virus, and can reduce the damage of the virus to the liver.
3) Stimulating liver cell regeneration with total glycosides of Cistanche deserticola can promote liver tissue regeneration and repair liver damage caused by hepatitis.
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